Effects of Moderate Intensity Aerobic Exercise on Blood Coagulation and Fibrinolysis in Post-Menopausal Hypertensive Women. | ||||
Egyptian Journal of Physical Therapy | ||||
Volume 17, Issue 1, March 2024 PDF (405.94 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejpt.2023.206056.1133 | ||||
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Authors | ||||
Ahmed Aref Ahmed 1; Tarek hanafy mahmoud 2; Mona Sayed Ahmed 3; Mohamed Yehia Gamal El-Din 4; Mohamed Abdelhameed Youdeif 5; Shymaa Abd Elhamed Salem 6 | ||||
1Department of integumentary physical therapy, Faculty of Physical Therapy, Deraya University, Minya, Egypt | ||||
2Department of Physical Therapy for Internal Medicine / Faculty of Physical Therapy, Deraya University, Minya, Egypt. | ||||
3Department of Physical Therapy for Pediatrics, Sphinx University, Assuit, Egypt. | ||||
4Department of basic science, Faculty of Physical Therapy, Deraya University Minya, Egypt. | ||||
5Department of Physical Therapy for Internal Medicine, chest, and Cardio, Faculty of Physical Therapy, Deraya University, Minya, Egypt. | ||||
6Department of Physical Therapy for neuromuscular disorders and its surgery, Faculty of Physical Therapy, Sphinx University, Assuit, Egypt. | ||||
Abstract | ||||
Abstract Objectives: This study was conducted to determine how postmenopausal hypertensive women’s blood coagulation and fibrinolysis parameters are affected by moderate-intensity aerobic exercise. Material and Methods: Fifty hypertensive female cases aged 50 to 65 took part in the trial, with BMIs ranging from 25 to 34.9 kg/m2. (Overweight and class 1 obesity). The cases were randomly allocated into the control and research groups. The control group (group A), which was under medical supervision, obtained anticoagulation medication. While the research group (group B) , which was under medical supervision, got anti-coagulation medication and moderately intense aerobic exercise in the form of three sessions each week for eight straight weeks of walking on an electronic treadmill for 40 to 50 minutes each sessions. Initial and two-month follow-up visits involve laboratory testing to measure clotting time, plasminogen activator inhibitor-1 (PAI-1), and to record systolic and diastolic blood pressure before and after the research. Results: Both groups’ clotting times markedly increased in favor of the study group by 7.01%, and the study group noticeably decreased PAI-1 (P< 0.05) compared to the control group by 19.18%. In contrast to the control group, the study group’s systolic and diastolic blood pressure were markedly lower (p< .05). Conclusion: In postmenopausal hypertensive women, moderate aerobic exercise markedly decreased arterial blood pressure and improved fibrinolysis by decreasing plasminogen activator inhibitor-1 (PAI-1) and lengthening the clotting time. | ||||
Keywords | ||||
Aerobic exercises; Plasminogen activator inhibitor -1; Fibrinolysis; postmenopausal hypertensive women | ||||
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