Evaluation of Therapeutic Effect of Spirulina in Patients with Geographic Tongue: A Randomized Double Blind Controlled Clinical Trial | ||||
| Egyptian Dental Journal | ||||
| Volume 70, Issue 2 - Serial Number 3, April 2024, Page 1223-1232 PDF (864.48 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/edj.2024.259856.2861 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Noha Nasr El-Zalabany   1; Ahmed Mohamed Badr 2; Olfat Shaker 3; Ahmed Adel Abdel-Azim 4
| ||||
| 1Lecturer of Oral Medicine and Oral Diagnosis, Faculty of Oral and Dental Surgery, Misr University for Science and Technology, Egypt | ||||
| 2Lecturer of Oral Medicine, Periodontology, Oral Diagnosis and Radiology, Faculty of Dentistry, Tanta University, Egypt | ||||
| 3Professor of Medical Biochemistry, Faculty of Medicine, Cairo University, Egypt. | ||||
| 4Lecturer of Oral Medicine and Oral Diagnosis, Faculty of Dentistry, Menoufia University, Egypt | ||||
| Abstract | ||||
| Abstract Objective: The aim of this study is to evaluate the therapeutic effect of spirulina in patients with Geographic Tongue Materials and Methods: Twenty patients diagnosed with symptomatic benign migratory glossitis will be selected. Research ethical committee will review the protocol and the procedure will be explained to the patients and they will sign an informed consent. Seven days after the diagnosis and selection of patients with (BMG), the atrophic areas will be determined and the patients will attend a control checkup in order to exclude those with constant changing patterns of the red atrophic areas with raised keratotic margins. The selected patient according the inclusion and exclusion criteria will be randomly allocated using computer generated allocation concealment into two groups; Group I (study group): Will include 10 patients with symptomatic BMG receiving Spirulina tablet Supplementation triple daily. Group II: Will include 10 patients with symptomatic BMG receiving placebo treatment for one month. (control group). Intensity of the discomfort will be monitored by the patients using the Visual Analogue Scale (VAS). Saliva will be collected from all included patients to evaluate interlukin -8 (IL -8). | ||||
| Keywords | ||||
| Spirulina; geographic tongue; Benign migratory glossitis; burning mouth syndrome; tongue inflammation | ||||
|
Statistics Article View: 45 PDF Download: 29 |
||||
