The effect of different instrumentation kinematics on the change in substance P levels in patients with symptomatic apical periodontitis. A randomized controlled trial
abdelbaset, S., Obeid, M., Fahmy, S. (2024). The effect of different instrumentation kinematics on the change in substance P levels in patients with symptomatic apical periodontitis. A randomized controlled trial. EKB Journal Management System, 70(2), 1837-1845. doi: 10.21608/edj.2024.252735.2812
salma abdelbaset; maram Obeid; Sarah Hossam Fahmy. "The effect of different instrumentation kinematics on the change in substance P levels in patients with symptomatic apical periodontitis. A randomized controlled trial". EKB Journal Management System, 70, 2, 2024, 1837-1845. doi: 10.21608/edj.2024.252735.2812
abdelbaset, S., Obeid, M., Fahmy, S. (2024). 'The effect of different instrumentation kinematics on the change in substance P levels in patients with symptomatic apical periodontitis. A randomized controlled trial', EKB Journal Management System, 70(2), pp. 1837-1845. doi: 10.21608/edj.2024.252735.2812
abdelbaset, S., Obeid, M., Fahmy, S. The effect of different instrumentation kinematics on the change in substance P levels in patients with symptomatic apical periodontitis. A randomized controlled trial. EKB Journal Management System, 2024; 70(2): 1837-1845. doi: 10.21608/edj.2024.252735.2812

The effect of different instrumentation kinematics on the change in substance P levels in patients with symptomatic apical periodontitis. A randomized controlled trial

Egyptian Dental Journal
Volume 70, Issue 2 - Serial Number 5, April 2024, Page 1837-1845  XML PDF (1.42 MB)
Document Type: Original Article
DOI: 10.21608/edj.2024.252735.2812
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Authors
salma abdelbaset email orcid 1; maram Obeidorcid 2; Sarah Hossam Fahmyorcid 3
1MSc student, Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egyp
2Professor, Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
3Lecturer, Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
Abstract
Aim: This study aimed to assess the influence of continuous rotation and reciprocation kinematics on the change in substance P (SP) levels in patients diagnosed with irreversible pulpitis and symptomatic apical periodontitis (SAP).

Materials and methods: A total of twenty patients were randomly assigned into two groups: Continuous Rotation Group (CG) (n=10), where mechanical preparation was performed with the EdgeEndox7 rotary system (Albuquerque, NM, USA), and Reciprocation Group (RG) (n=10), with EdgeOne Fire reciprocating system (Albuquerque, NM, USA). Apical fluid (AF) samples were collected and changes in SP levels were quantified through ELISA. Data were statistically analyzed utilizing the independent t-test, Friedman’s test, and Nemenyi post hoc test.

Results: The difference of SP levels in the reciprocating group was significantly higher when compared to the continuous rotation group (P≤ 0.05) when measured preoperatively and at the beginning of the second visit.

Conclusion: Our findings suggest that continuous rotation kinematics lead to a reduction in substance P levels.
Keywords
continuous rotation; reciprocation; substance P; apical periodontitis
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