The effect of Propolis Nanoparticles irrigation on reduction of bacterial Endotoxins A Randomized Clinical Trial | ||||
| Egyptian Dental Journal | ||||
| Volume 70, Issue 2 - Serial Number 5, April 2024, Page 2151-2157 PDF (610.03 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/edj.2024.272758.2956 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Fatma ElZahraa ElAbbasy  
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| Endodontic Department, Faculty of Dentistry, Cairo University | ||||
| Abstract | ||||
| Aim: The aim of this study was to evaluate the effect of propolis nanoparticles irrigating solution versus sodium hypochlorite on reduction of bacterial endotoxins. Materials and Methods: Forty-five single rooted non-vital permanent maxillary anterior teeth with tenderness to percussion and slight widening of lamina dura in medically free patients were included in the study. The patient's age ranged from 20-50 years, either males or females. Patients were randomly divided into three groups, 15 patients in each group, Group (1): 0.9% saline solution, Group (2): 2.5 % sodium hypochlorite (NaOCl) and Group (3): 20% Propolis nanoparticles. Two samples were taken for each group using paper points, one after access cavity preparation (S1) and the second sample after irrigation (S2). Samples were placed in a pyrogen free glass tube and stored at -20 degree Celsius then were assessed for quantification of bacterial endotoxins using ELISA kit, and subjected to statistical analysis. Results: Results showed that the use of 20% propolis nanoparticles as a root canal irrigant resulted in significantly higher reduction of endotoxins level compared to 2.5% NaOCl root canal irrigation. Conclusion: It could be concluded that the use of 20% propolis nanoparticles root canal irrigation allowed more reduction of endotoxins level significantly, compared to 2.5% NaOCl irrigation. | ||||
| Keywords | ||||
| Sodium Hypochlorite; Propolis; Irrigation; Endotoxins; Enterococcus faecalis | ||||
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