Evaluation of the Antibacterial Activity, Solubility and Ions Release of Compomer before and after the Addition of 0.025 ml Silver Nanoparticles: An In-Vitro Study
Tawfik, L., Sabry, H., Amin, A. (2024). Evaluation of the Antibacterial Activity, Solubility and Ions Release of Compomer before and after the Addition of 0.025 ml Silver Nanoparticles: An In-Vitro Study. EKB Journal Management System, 6(2), 252-261. doi: 10.21608/adjc.2023.223816.1371
Laila Mahmoud Tawfik; Hadil Ahmed Sabry; Abdel Hadi Mohmaed Amin. "Evaluation of the Antibacterial Activity, Solubility and Ions Release of Compomer before and after the Addition of 0.025 ml Silver Nanoparticles: An In-Vitro Study". EKB Journal Management System, 6, 2, 2024, 252-261. doi: 10.21608/adjc.2023.223816.1371
Tawfik, L., Sabry, H., Amin, A. (2024). 'Evaluation of the Antibacterial Activity, Solubility and Ions Release of Compomer before and after the Addition of 0.025 ml Silver Nanoparticles: An In-Vitro Study', EKB Journal Management System, 6(2), pp. 252-261. doi: 10.21608/adjc.2023.223816.1371
Tawfik, L., Sabry, H., Amin, A. Evaluation of the Antibacterial Activity, Solubility and Ions Release of Compomer before and after the Addition of 0.025 ml Silver Nanoparticles: An In-Vitro Study. EKB Journal Management System, 2024; 6(2): 252-261. doi: 10.21608/adjc.2023.223816.1371

Evaluation of the Antibacterial Activity, Solubility and Ions Release of Compomer before and after the Addition of 0.025 ml Silver Nanoparticles: An In-Vitro Study

Advanced Dental Journal
Volume 6, Issue 2, April 2024, Page 252-261  XML PDF (513.77 K)
Document Type: Original Article
DOI: 10.21608/adjc.2023.223816.1371
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Authors
Laila Mahmoud Tawfik email 1; Hadil Ahmed Sabry2; Abdel Hadi Mohmaed Amin1
1Biomaterials Department, Faculty of Dentistry, Cairo University, Egypt
2Biomaterials Department, Faculty of Dentistry, October 6 University, Egypt
Abstract
Aim: Evaluate the effect of silver nanoparticles addition on antibacterial activity, solubility and ions release of compomer at different time intervals. Methodology: 0.025 ml nanosilver alcohol solution (5000 ppm) was mixed with 2 g of Composan glass (compomer material). Composan glass without nanosilver was used as the control group. Total of 48 disc-shaped samples(15x1mm) were prepared and immersed in distilled water for 24 hours, 1 and 3 months. After each time interval, samples were assessed for antibacterial activity by Agar Diffusion Test using Streptococcus mutans. Water sorption and solubility were evaluated by weighting the samples before and after immersion. Fluoride Ion-Selective Electrode determined fluoride release while Inductively Coupled Plasma-Mass Spectrometer measured silver ion release.
Results: The experimental group showed significantly higher inhibition zones for all follow-up results. For water sorption test, the higher values were in the experimental group after 1 and 3 months. While for the solubility the higher values were in the experimental group after all follow-ups. Regarding fluoride ion release, comparison between both groups showed no significant difference after all follow-ups. For the silver ion release, results showed significant difference regarding all follow-ups with higher values in the experimental group. Conclusions: Compomers incorporated with 0.025ml silver nanoparticles is promising antibacterial restoration against Streptococcus mutans.
Keywords
Compomer; Silver Nanoparticles; Antibacterial Activity; Solubility; Ions Release
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