Association of Hypoalbuminemia in Preeclampsia with Maternal and Perinatal Outcomes | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 42, Volume 95, Issue 1, April 2024, Page 1550-1558 PDF (509.28 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2024.350103 | ||||
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| Abstract | ||||
| Background: Preeclampsia-eclampsia (PE) accounts for 18% of maternal mortality globally, with a frequency of 5–10%. Increased capillary permeability brought on by proteinuria and endothelial degradation reduces albuminemia in PE. Interstitial edema and a drop in blood volume are caused by a reduction in colloid osmotic pressure (PCO), which activates the renin-angiotensin-aldosterone pathway. Aim: To analyze and appraise the outcomes for mothers and babies in preeclampsia (PE) based on serum albumin levels. Patients and Methods: At Al Hussein University Hospital, a prospective cross-sectional study was carried out from June to December of 2023. 100 pregnant women with preeclampsia participated in the study. The women were split into two groups: group A had mild hypoalbuminemia with an albumin value of ≤25g/L and group B had severe hypoalbuminemia. Results: There was significant difference in mild hypoalbuminemia at different times regarding serum albumin that was lower at 35 weeks than 26 weeks and 6-9 weeks and dipstick albuminuria that was higher at 35 weeks than 26 weeks and 6-9 weeks. Also, there was significant difference in severe hypoalbuminemia group at different times regarding serum albumin that was lower at 35 weeks than 26 weeks and 6-9 weeks and dipstick albuminuria that was higher at 35 weeks than 26 weeks and 6-9 weeks. Conclusion: Pregnancy should be closely monitored for severe hypoalbuminemic pre-eclampsia since it is linked to a higher risk of negative outcomes for both the mother and the newborn than mild hypoalbuminemic pre-eclampsia. | ||||
| Keywords | ||||
| Hypoalbuminemia; Preeclampsia; Maternal | ||||
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