Role of Diffusion Weighted Imaging & Dynamic Contrast Enhanced Magnetic Resonance Imaging in Assessment of Asymmetric Breast Densities | ||||
| Zagazig University Medical Journal | ||||
| Article 17, Volume 26, Issue 2, March 2020, Page 335-343 PDF (1.1 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zumj.2019.11327.1183 | ||||
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| Authors | ||||
Hajer Abushaafa Abdalla   1; Hazem M. El Shahat Mousa1; ghada El Sayied Abdulmonaem1; Dena Abd El Aziz El Sammak2
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| 1Department of Radiodiagnosis, Faculty of Medicine, Zagazig University, Zagazig, Egypt | ||||
| 2Radio diagnosis Department, Faculty of Medicine, Zagazig University | ||||
| Abstract | ||||
| Abstract Objective: The aim of the study is to determine the diagnostic value of both DCE-MRI & DW-MRI in assessment of cases with mammographic asymmetrical breast densities. Methods: This study was carried out at Radiodiagnosis Department, Zagazig University Hospitals, on 29 patients with breast asymmetry. Diagnostic work up included Mammography, US, & MRI. Results: The study included 29 females with mammographic breast asymmetry, 17 were having global asymmetry, while 12 with focal asymmetry.65.52% of asymmetry in this study was due to benign causes while 34.48% was due to malignant causes, DCE-MRI provided special characterization of lesions by their morphology & dynamic enhancement with 90% sensitivity 84.21% specificity, & 86.2% accuracy. DWI & ADC value provided differentiation between malignant & benign lesions, malignant lesions showed restricted diffusion with lower ADC values than benign lesions, the mean ADC value for benign lesions was (1.4±0.45x10-3sec/mm2), & the mean ADC value for malignant lesions was (0.85±0.29x10-3sec/mm2), & the cutoff ADC value was ( | ||||
| Keywords | ||||
| Breast; DWI; DCE-MRI; Breast MRI | ||||
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