INTRA-ARTICULAR REGENERATIVE INJECTION FOR MANAGEMENT OF PAINFUL IRREDUCIBLE TEMPOROMANDIBULAR DISC DISPLACEMENT
Bahgat, M., EL-Helw, N., Abdelhamid, A., Fata, M., Ashour, M., Atteya, A. (2024). INTRA-ARTICULAR REGENERATIVE INJECTION FOR MANAGEMENT OF PAINFUL IRREDUCIBLE TEMPOROMANDIBULAR DISC DISPLACEMENT. EKB Journal Management System, (), -. doi: 10.21608/adjalexu.2023.201880.1362
Mariam M. Bahgat; Nadia R. EL-Helw; Ahmed M. Abdelhamid; Mohamed M. Fata; Medhat S. Ashour; Aly Atteya. "INTRA-ARTICULAR REGENERATIVE INJECTION FOR MANAGEMENT OF PAINFUL IRREDUCIBLE TEMPOROMANDIBULAR DISC DISPLACEMENT". EKB Journal Management System, , , 2024, -. doi: 10.21608/adjalexu.2023.201880.1362
Bahgat, M., EL-Helw, N., Abdelhamid, A., Fata, M., Ashour, M., Atteya, A. (2024). 'INTRA-ARTICULAR REGENERATIVE INJECTION FOR MANAGEMENT OF PAINFUL IRREDUCIBLE TEMPOROMANDIBULAR DISC DISPLACEMENT', EKB Journal Management System, (), pp. -. doi: 10.21608/adjalexu.2023.201880.1362
Bahgat, M., EL-Helw, N., Abdelhamid, A., Fata, M., Ashour, M., Atteya, A. INTRA-ARTICULAR REGENERATIVE INJECTION FOR MANAGEMENT OF PAINFUL IRREDUCIBLE TEMPOROMANDIBULAR DISC DISPLACEMENT. EKB Journal Management System, 2024; (): -. doi: 10.21608/adjalexu.2023.201880.1362

INTRA-ARTICULAR REGENERATIVE INJECTION FOR MANAGEMENT OF PAINFUL IRREDUCIBLE TEMPOROMANDIBULAR DISC DISPLACEMENT

Alexandria Dental Journal
Articles in Press, Corrected Proof, Available Online from 18 April 2024  XML PDF (320.62 K)
Document Type: Original Article
DOI: 10.21608/adjalexu.2023.201880.1362
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Authors
Mariam M. Bahgat email orcid 1; Nadia R. EL-Helw2; Ahmed M. Abdelhamid2; Mohamed M. Fata3; Medhat S. Ashour4; Aly Atteyaorcid 5
1Assistant Lecturer of Prosthodontics, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
2Department of Prosthodontics, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
3Department of Maxillofacial and Plastic Surgery, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
4Department of Microbiology, High Institute of Public Health, Alexandria University, Alexandria, Egypt.
5Lecturer of Maxillofacial and Plastic Surgery, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
Abstract
Introduction: Nearly all of non-dental related chronic orofacial pain problems are temporomandibular disorders (TMDs). TMDs are associated with joint pain, sounds and limitation of mandibular movements. Although TMDs are not life threatening conditions; nevertheless they negatively affect the patients’ quality of life making the treatment necessary.
Objective: To assess the effect of intra-articular injection of liquid phase concentrated growth factors (LPCGF), in patients with restricted mouth opening associated with irreducible disc displacement (DDwR).

Methodology: 12 patients with painful DDwR and limited mouth opening were enrolled in the study. Patients received an intra-articular injection of 2ml LPCGF with a 3D printed stabilization appliance (SA). The patients’ symptoms were assessed clinically through Helkimo Anamnestic dysfunction index (Ai) and the maximum mouth opening (MMO) was measured at baseline as well as 1 week, 4 weeks, and 12 weeks post-treatment.

Results: There was a significant relief in symptoms at the 4, and 12 weeks follow-up periods (p = 0.001, p < 0.001 respectively). The mean of MMO at the baseline was 31.75 mm, while 1 week after the injection it was significantly increased to 33.50 mm (p <0.001).Moreover, by 12 weeks, the MMO was significantly improved (37.50 ± 2.54; p <0.001).

Conclusion: Intra-articular injection of LPCGF and SA could be considered a management protocol for patients suffering from DDwR as it relieved TMD symptoms and increased the MMO.
Keywords
Temporomandibular disorders; Internal derangement; Growth Factors; Regenerative injection; Maximum mouth opening
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