INTRA-ARTICULAR REGENERATIVE INJECTION FOR MANAGEMENT OF PAINFUL IRREDUCIBLE TEMPOROMANDIBULAR DISC DISPLACEMENT | ||
| Alexandria Dental Journal | ||
| Article 6, Volume 49, Issue 2, August 2024, Pages 158-163 PDF (320.77 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/adjalexu.2023.201880.1362 | ||
| Authors | ||
| Mariam M. Bahgat* 1; Nadia R. EL-Helw2; Ahmed M. Abdelhamid2; Mohamed M. Fata3; Medhat S. Ashour4; Aly Atteya5 | ||
| 1Assistant Lecturer of Prosthodontics, Faculty of Dentistry, Alexandria University, Alexandria, Egypt. | ||
| 2Department of Prosthodontics, Faculty of Dentistry, Alexandria University, Alexandria, Egypt. | ||
| 3Department of Maxillofacial and Plastic Surgery, Faculty of Dentistry, Alexandria University, Alexandria, Egypt. | ||
| 4Department of Microbiology, High Institute of Public Health, Alexandria University, Alexandria, Egypt. | ||
| 5Lecturer of Maxillofacial and Plastic Surgery, Faculty of Dentistry, Alexandria University, Alexandria, Egypt. | ||
| Abstract | ||
| Introduction: Nearly all of non-dental related chronic orofacial pain problems are temporomandibular disorders (TMDs). TMDs are associated with joint pain, sounds and limitation of mandibular movements. Although TMDs are not life threatening conditions; nevertheless they negatively affect the patients’ quality of life making the treatment necessary. Objective: To assess the effect of intra-articular injection of liquid phase concentrated growth factors (LPCGF), in patients with restricted mouth opening associated with irreducible disc displacement (DDwR). Methodology: 12 patients with painful DDwR and limited mouth opening were enrolled in the study. Patients received an intra-articular injection of 2ml LPCGF with a 3D printed stabilization appliance (SA). The patients’ symptoms were assessed clinically through Helkimo Anamnestic dysfunction index (Ai) and the maximum mouth opening (MMO) was measured at baseline as well as 1 week, 4 weeks, and 12 weeks post-treatment. Results: There was a significant relief in symptoms at the 4, and 12 weeks follow-up periods (p = 0.001, p < 0.001 respectively). The mean of MMO at the baseline was 31.75 mm, while 1 week after the injection it was significantly increased to 33.50 mm (p <0.001).Moreover, by 12 weeks, the MMO was significantly improved (37.50 ± 2.54; p <0.001). Conclusion: Intra-articular injection of LPCGF and SA could be considered a management protocol for patients suffering from DDwR as it relieved TMD symptoms and increased the MMO. | ||
| Keywords | ||
| Temporomandibular disorders; Internal derangement; Growth Factors; Regenerative injection; Maximum mouth opening | ||
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