AN OVERVIEW ON INTESTINAL PARASITES AND GUT MICROBIOME: A BIDIRECTIONAL RELATIONSHIP | ||||
| Journal of the Egyptian Society of Parasitology | ||||
| Article 2, Volume 54, Issue 1, April 2024, Page 1-10 PDF (767.9 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jesp.2024.351281 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| GHADA A. SAAD; HALA E. SHAMS EL-DIN | ||||
| Department of Medical Parasitology, Faculty of Medicine, Ain Shams University, Cairo 11566, and Badr University in Cairo (BUC), Egypt | ||||
| Abstract | ||||
| The human body hosts a vast and diverse ecosystem known as the microbiota, inclusive of bacteria, viruses, archaea, and parasites. The majority of gut microbiota resides in the colon, with Firmicutes and Bacteroidetes representing the predominant phyla. Disruption of gut microbiota (dysbiosis) is associated with various intestinal and systemic diseases. Development of intestinal parasitic infections may alter bacterial composition, immune responses, and homeostatic relationships within the gut ecosystem. Protozoa, like Giardia intestinalis, Entamoeba histolytica, and Blastocystis cause interactions with resident bacteria, impacting the microbiota's composition and diversity. Toxoplasma gondii influences gut microbiota leading to changes in bacterial load, diversity and translocation. Owing to their immunomodulatory effects, helminths as Trichuriasis exhibit potential control of autoimmune diseases. The relationship between the gut microbiome and intestinal parasites is intricate and dynamic. The microbiome can influence parasitic infections, affecting immune responses and disease outcomes. | ||||
| Keywords | ||||
| Gut microbiota; Intestinal parasites; Dysbiosis; An overview | ||||
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