Bacterial Biofilm in Chronic Suppurative Otitis Media | ||||
| Sohag Medical Journal | ||||
| Volume 28, Issue 2., 2024, Page 100-107 PDF (601.84 K) | ||||
| Document Type: Review Article | ||||
| DOI: 10.21608/smj.2024.233730.1414 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Alaa Ezzat Ahmed  1; abeer shneef mohamed2; Asmaa mohamed Goda3; Khaled Abd Elrahman Ali4
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| 1Microbiology,faculty of medicine ,sohag university, sohag | ||||
| 2Department of Medical Microbiology and Immunology, Sohag Faculty of Medicine, Sohag University | ||||
| 3Microbiology | ||||
| 4Department of Otolaryngology,Faculty of medicine, Sohag university Sohag | ||||
| Abstract | ||||
| One of the most prevalent inflammatory lesions in the specialty of otorhinolaryngology is chronic suppurative otitis media (CSOM). A chronic suppurative inflammatory reaction of the middle ear mucosa and tympanic membrane, known as chronic suppurative otitis media, frequently invades middle ear tissues such the tympanum, mastoid process, tympanic sinus, and eustachian tube. Tympanic membrane perforation, hearing loss, and intermittent or persistent pus discharge in the ear are the most prevalent clinical signs of this illness. Microbes living in tightly clustered, slowly expanding microcolonies and encased in a matrix made of a protective biopolymer form biofilm. The microorganisms develop the highest degrees of immunity to antibiotics and the immune system in biofilms. The middle ear cavity's bacterial biofilm may serve as a reservoir for the bacteria that cause recurring or chronic ear discharge in patients with CSOM. The benefits of controlling this form of infection, its impacts and complications, and preventing the emergence of antibiotic resistance may result from the successful elimination of such bacterial behavior. | ||||
| Keywords | ||||
| Keywords: Chronic suppurative otitis media; Biofilm; Antibiotic resistance | ||||
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