The value of PET/CT combined with complementary MRI in the follow-up of hepatocellular carcinoma after transarterial chemoembolization. | ||||
Ain Shams Medical Journal | ||||
Volume 75, Issue 1, March 2024, Page 141-150 PDF (741.01 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/asmj.2023.244158.1179 | ||||
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Authors | ||||
Ahmed Fathy Abdou Elhadad ![]() ![]() | ||||
1Ismailia general Hospital - Ismailia -Ministry of health, Egypt. | ||||
2Radiology department, Faculty of Medicine, Ain shams University, Cairo, Egypt. | ||||
3Department of Radiodiagnosis, Faculty of Medicine - Ain Shams University, Egypt. | ||||
Abstract | ||||
Background: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and the third leading cause of cancer-related death worldwide. Aim of the work: To assess the potential value of combining PET/CT and complementary MRI in the follow-up of HCC treated by trans-arterial chemo-embolization (TACE). Patients and Methods: This prospective study was done including forty patients having HCC treated by TACE. These patients were examined by 18F-FDG PET/CT combined with complementary MRI. PET/CT and MRI findings were analyzed. As a result, the included patients were divided into four groups; true positive, true negative, false negative and false positive. Serial alpha-fetoprotein levels were also reviewed. Results: By combining PET/CT and MRI findings, results were true positive in 14 patients, true negative in 14 patients, false negative in 9 patients and false positive in 3 patients. Consequently, true results represented 70%; whereas, false results represented 30%. Conclusion: The combination of PET/CT and complementary MRI did not have any added value in the follow-up of HCC after TACE. | ||||
Keywords | ||||
18F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT); Magnetic resonance imaging (MRI); Hepatocellular carcinoma (HCC); trans-arterial chemo-embolization (TACE); Alpha-fetoprotein (AFP) | ||||
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