Overview on synthetic strategies and bioactivities of pyrazolopyridines. | ||||
| Egyptian Journal of Chemistry | ||||
| Articles in Press, Accepted Manuscript, Available Online from 13 May 2024 | ||||
| Document Type: Review Articles | ||||
| DOI: 10.21608/ejchem.2024.281932.9564 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Manal Ezzat   1; Heba Allam 2; Samy Mohamady 3; samar Mogheith4
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| 1Faculty of Pharmacy, Cairo University, Cairo, Egypt. | ||||
| 2Faculty of Pharmacy, Cairo University | ||||
| 3Pharmaceutical Chemistry Department, Faculty of Pharmacy, BUE | ||||
| 4Faculty of Pharmacy, BUE | ||||
| Abstract | ||||
| There is undeniable evidence that many N-heterocycles exhibit a wide range of biological functions. Recently, derivatives with better bioactivities have been generated by condensing the different heterocycles. Pyrazolopyridines have been able to pique the interest of many researchers among many other condensed heterocycles, due to the wide range of actions they exhibit. Furthermore, each type of condensed heterocycle has been specifically highlighted in this review in terms of design and biological activities. In silico methods and structure-activity relationship have also been discussed wherever reported. | ||||
| Keywords | ||||
| Pyrazolopyridines; biological activities; SAR; Target; Kinase | ||||
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