Autoimmunity & Type 1 diabetes patients: Review Article | ||||
| SVU-International Journal of Medical Sciences | ||||
| Article 78, Volume 7, Issue 1, January 2024, Page 782-788 PDF (197.27 K) | ||||
| Document Type: Reviews Articles. | ||||
| DOI: 10.21608/svuijm.2022.156374.1379 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Khaled A. Abdel Baseer* 1; Abdallah E. Mohammed* 2; Aya Mohammed Abo Elwafa  1; Hala M. Sakhr* 1
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| 1Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, Egypt | ||||
| 2Department of Clinical Pathology , Faculty of Medicine, South Valley University, Qena, Egypt. | ||||
| Abstract | ||||
| Background: Increased blood glucose levels (hyperglycemia) are a hallmark of type 1 diabetes mellitus (T1DM), a chronic autoimmune illness marked by insulin insufficiency as a result of the destruction of the pancreatic islet cells. T1DMs a widespread metabolic disorder in children. The loss of cells is due to autoimmunity in mostndividuals (70-90%) with T1DM(concomitant with the formation of T1DM-associated autoantibodies). Autoantibodies are often detected months or even years before the start of symptoms in people with T1DM. These autoantibodies are indicators of the onset of autoimmunity rather than pathogens. Many autoimmune diseases have symptoms of T1DM. Such factors may profoundly impact clinical care of the illness, particularly in children. The four most common autoimmune disorders are vitiligo, Addison's disease, celiac disease, and autoimmune thyroid disease. Objectives: To outline the association of T1DM as an autoimmune disease with other comorbid autoimmune illnesses Conclusion: Several endocrine and non-endocrine autoimmune diseases are strongly linked to type 1 diabetes mellitus. | ||||
| Keywords | ||||
| Autoimmune disease; Type 1 diabetes mellitus; Celiac disease; Autoimmune thyroid disease; Addison’s disease; Vitiligo | ||||
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