Cross Sectional Study of Acute Toxicity with Anti Diabetic Drugs in Patients Presented to Poisoning Center During 2022 | ||||
| Egyptian Society of Clinical Toxicology Journal | ||||
| Volume 12, Issue 1, June 2024, Page 136-147 PDF (622.25 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/esctj.2024.285519.1057 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Marwa Issak Mohamed1; Amal Salama Mahmoud   2; Sara Mahmoud Emam Mohamed3; Nermin Hamdy Mohamed4; Walaa Abdel-hady Abdel-halim5
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| 1department of forensic medicine &clinical toxicology , Cairo university | ||||
| 2department of forensic medicine & clinical toxicology, faculty of medicine, Cairo university | ||||
| 3department of forensic medicine & clinical toxicology, faculty of medicine, Cairo university | ||||
| 4Department of Occuptional and Environmental Medicine, Cairo University | ||||
| 5Department of Forensic Medicine and Clinical Toxicology Faculty of Medicine, Cairo University | ||||
| Abstract | ||||
| Background: Toxicity from anti diabetic drugs may occur for many reasons accidental and suicidal. Some patients deliberately overdose on medications. In other cases, therapeutic misadventures and medication administration errors cause unintentional poisoning. Aim of the work: The aim of this study is to identify the incidence of anti diabetic drugs acute toxicity in patients presented to National Environmental and Clinical Toxicology and Research Center, Cairo university “Cairo and Giza governorates”, During 2022 (From January to December 2022). To give an idea about demographic data (age, sex, residence, and marital status), circumstances of toxicity, common clinical presentations, severity of the toxicity, management plan and final outcome. Subjects and Methods: The study included 100 cases who were admitted at NECTR during 2022. Cases were analyzed regarding demographic data, circumstances of toxicity, common clinical presentations, severity of the toxicity, management plan, and final outcome. Results: The most common types of anti diabetic drugs toxicity are bigunaides and insulin. Most cases were not diabetic, were suicidal attempts, stayed from 24 to 72 hours in the hospital and discharged on their own responsibility. In this study; 88 case was >18 years, 89 patients were Females; 95 case were urban residents; 54 cases were married; 84 cases were non-working, Metformin was the most common type of antidiabetic drugs toxicity (73 case). Conclusions: Anti-diabetic drug toxicity is a critical issue that may be suicidal, accidental. | ||||
| Keywords | ||||
| Anti-diabetic drugs; Intoxication; Hypoglycemia; NECTR | ||||
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