Plasma Metabolomics in Mice After Treatment by Structure Nano-Lipid SNL PGF2α and PMSG during Synchronization and Superovulation Protocol in Mice | ||||
Egyptian Journal of Veterinary Sciences | ||||
Volume 56, Issue 6, June 2025, Page 1247-1254 PDF (932.63 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejvs.2024.282292.1995 | ||||
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Authors | ||||
buthina abdalhameed abdullah 1; Mohanad A. Al-Bayati2 | ||||
11Physiology and Pharmacology Department, Veterinary Medicine Collage, University of Tikrit, Iraq | ||||
2Physiology and Pharmacology Department, Veterinary Medicine Collage, University of Baghdad, Iraq | ||||
Abstract | ||||
Metabolomics is the study of metabolites, small molecule intermediates, and metabolites. We report the metabolomics in the plasma of mice administered SNL PGF2α and PMSG during synchronized and super ovulated protocols. Groups of 3 female Albino mice were each treated first group PGF2α 14.7 µg\kg BW. and PMSG 8.3 IU\kg BW. while second group SNL PGF2α 6.6 µg\kg BW. and PMSG 8.3 IU\kg BW. and, there group. The control group received no treatment. Metabolites in plasma were extracted with methanol-chloroform-water and identified by gas chromatography-mass spectrometry (GC Mass). The remarkable markers of candidates groups of plasma provide 221 total number in conventional were 76, in control 75 metabolomics, while in SNL 72 metabolomics when comparing between the groups in the conventional group higher than other groups. | ||||
Keywords | ||||
Metabolomics; Synchronization; Superovulation; SNL; GC Mass | ||||
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