Role of autophagy in immune regulation | ||||
Sohag Medical Journal | ||||
Article 39, Volume 22, Issue 3, October 2018, Page 329-331 PDF (38.98 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/smj.2018.36151 | ||||
View on SCiNiTO | ||||
Authors | ||||
Marwa Hashim1; Nesma Mohamed2; Ekram Mahmoud3 | ||||
1Department of Biochemistry and microbiology, Facaulty of Medicine, Sohag University. | ||||
2Department of Biochemistry and microbiology, Faculty of Medicine, Sohag university. | ||||
3Department of Biochemistry and microbiology, Faculty of Medicine, Sohag university | ||||
Abstract | ||||
Autophagy is a highly conserved protein degradation pathway responsible for removal of damaged organelles, malformed proteins during biosynthesis, and nonfunctional long-lived proteins by lysosome. Autophagy has been divided into three general types depending on the mechanism by which intracellular materials are delivered into lysosome for degradation that is, microautophagy, chaperone mediated autophagy (CMA), and macroautophagy. Numerous studies reveal autophagy and autophagy related proteins also participate in immune regulation. in this review we summarized current understanding of the roles of autophagy and autophagy proteins in immune regulation. | ||||
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