Sequelae of Adjuvant Irradiation of Breast Cancer on the Shoulder Region (Influence of Different Doses and Techniques) | ||||
| Minia Journal of Medical Research | ||||
| Articles in Press, Accepted Manuscript, Available Online from 24 June 2024 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjmr.2024.295294.1720 | ||||
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| Authors | ||||
Nada Hussein Ali Sholkami1; Wafaa Mohamed Abdel-Latif2; Maram Abdelhakim Farouk  3; Ahmad Mostafa Abdel-Azeez4
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| 1Department of clinical oncology | ||||
| 2department of clinical oncology | ||||
| 3Clinical Oncology and nuclear medicine Department ,Faculty of medicine , Minia University. | ||||
| 4Clinical Oncology and Nuclear Medicine Department ,Faculty of medicine , Minia University. | ||||
| Abstract | ||||
| Introduction :Globally, breast cancer (BC) is the most frequently diagnosed cancer; about 2.2 million new cases are expected to be diagnosed with BC in 2020. Furthermore, with over 680,000 deaths, it is the primary cause of cancer-related mortality among women. (Sung and others, 2021). Multim odalities have been described in treatment of breast cancer ; surgery , chemotherapy , hormonal therapy , targeted therapy and radiotherapy . In addition, adverse effects from breast cancer treatment could include fibrosis, shoulder and arm pain, limited movement, and breast cancer-related lymphedema (BCRL). Breast cancer patients' arm pain has been linked mostly to radiation therapy (RT) (Hopwood et al.,2010) Subjects and Methods: The female patients over the age of eighteen who had primary breast cancer and metastasized to the axillary lymph nodes underwent adjuvant regional nodal irradiation (RNI) in this retrospective longitudinal research. Minia University Hospital (MUH) provided the data, which were gathered between 2017 and 2022. The American Joint Committee on Cancer (AJCC 2018) TNM staging approach was utilized to stage the patients, and immunohistochemistry was employed for molecular categorization. Results: Relation between shoulder affection and weight , age , median dose of radiation to the shoulders and number of lymph nodes dissected. Conclusion :There was a correlation between the mean radiation dose and the volume of the shoulder receiving doses of 10 Gy, 20 Gy, and 30 Gy, as well as shoulder affection following radiotherapy, in addition to the patient's age, weight, and surgical dissection of the axillary lymph nodes. | ||||
| Keywords | ||||
| breast; radiotherapy; shoulder | ||||
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