Frequency of Hepatitis C Virus Infection in Vitiligo Patients at Qena University Hospital | ||||
| SVU-International Journal of Medical Sciences | ||||
| Volume 7, Issue 2, July 2024, Page 183-188 PDF (99.36 K) | ||||
| Document Type: Original research articles | ||||
| DOI: 10.21608/svuijm.2024.262409.1778 | ||||
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| Authors | ||||
shimaa Arafat Abdel-Monem   1; Soheir Abdel-hamid Ali2
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| 1Tropical Medicine and Gastroenterology, Faculty of Medicine, South Valley University, Qena, Egypt | ||||
| 2Dermatology, Venereology and Andrology, Faculty of Medicine, South Valley University, Qena, Egypt | ||||
| Abstract | ||||
| Background: A range of autoimmune illnesses may be accelerated by hepatitis C virus (HCV). It is yet unclear how HCV infection and vitiligo are related. However, autoimmune pathways may be involved. Objectives: In this study, we estimated the frequency of HCV sero-positivity in patients with vitiligo and compared it to the population without vitiligo. Patients and methods: A total of 70 vitiligo patients and 70 control non vitiligo-patients were included in this study serum anti-HCV antibodies were measured using HCV third generation ELISA. The total body Vitiligo Area Scoring Index (VASI) is calculated. Results: vitiligo patients (mean age: 33.04 ±18.93 years), control population (mean age 30±16.8 years) (41 males, 29 females), and 70 control population were (30 males, 40 females). The mean age was (33.04 ± 18.93). About 15 (21.4) of patients were employees, and 58.6% were from rural areas. Fifty percent were single. The mean duration of illness in all vitiligo patients is about (5.6 ± 5.1 years) (VASI) (3.66 ± 0.77). The control population was 70 with age and sex-matched (30 males, 40 females, mean age 30 ± 16.8 years. The anti-HCV antibody in vitiligo patients and all controls were negative. Conclusion: The sero-prevalence of HCV in individuals with vitiligo is not different from that of a control group, suggesting that HCV infection may not play a role in the pathophysiology of those patients. | ||||
| Keywords | ||||
| Autoimmune; Virus; Sero-prevalence | ||||
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