Assessment of Secondary Hyperparathyroidism as a Cause of Pulmonary Hypertension among End Stage Renal Disease Patients on Regular Hemodialysis | ||||
| Medicine Updates | ||||
| Volume 18, Issue 18, July 2024, Page 87-104 PDF (965.74 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/muj.2024.299843.1173 | ||||
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| Authors | ||||
Abd El Rahman Badra  1; Mamdouh El-Nahas2; Amir Okeely3; Hanzada Elmaghrabi4
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| 1Internal Medicine and Nephrology Department; port fouad hospital | ||||
| 2internal medicine Faculty of medicine Port Said University | ||||
| 3Internal Medicine & Nephrology Faculty of Medicine – Zagazig University | ||||
| 4Internal Medicine and Nephrology Department; Faculty of Medicine, Port Said University | ||||
| Abstract | ||||
| Background: End-stage renal disease can result in several systemic consequences that pose a significant risk to life, such as cardiovascular disorders. Pulmonary arterial hypertension, characterized by increased blood pressure in the pulmonary artery, poses a significant risk for both morbidity and mortality in individuals with end-stage renal disease (ESRD). Aim of the study: The aim of the current study was to evaluate association between hyperparathyroidism and incidence of pulmonary hypertension among haemodialysis patients. Methods: This study was performed on 100 haemodialysis patients; they were divided according to incidence of pulmonary hypertension into 2 groups: 63 pulmonary hypertension patients and 37 patients without pulmonary hypertension. Results: The most reported leading cause of end- stage renal disease was hypertension (65%), analgesic nephropathy (11%) and diabetic nephropathy (9%). About 27% of patients had residual urine output.The included patients received hemodialysis for about 3.06 ± 1.5 years with average ultrafiltration rate 3.3 ± 1.15 L. About 96% of patients received hemodialysis via A- v fistula and mean A- v fistula flow volume was 1111.7 ± 434.1. Conclusion: Disturbance in parathyroid release significantly affected incidence of pulmonary hypertension. Also, hypoparathyroidism is associated with increased incidence rate of pulmonary hypertension. | ||||
| Keywords | ||||
| chronic kidney disease; end-stage renal disease; haemodialysis; hyperparathyroidism; pulmonary hypertension. | ||||
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