Recurrent orbital solitary fibrous tumor: clinical and pathological insights from a Case Report and literature review

Toubi, Zakaria; FADEL, REDA; El Amine EL Alami, Mohamed Noureddine; Kamal, Dounia

doi:10.21608/omx.2024.276066.1232

	Recurrent orbital solitary fibrous tumor: clinical and pathological insights from a Case Report and literature review
Egyptian Journal of Oral and Maxillofacial Surgery
Volume 15, Issue 3, July 2024, Page 126-130 PDF (642.08 K)
Document Type: Case Report
DOI: 10.21608/omx.2024.276066.1232
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Authors
Zakaria Toubi ¹; REDA FADEL¹; Mohamed Noureddine El Amine EL Alami²; Dounia Kamal³
¹Oral and maxillo facial surgery department, Hassan II University Hospital, Sidi Mohamed Ben Abdellah University, Faculty of Medicine and Pharmacy, Fez, Morocco
²Oral and maxillofacial surgery department, Hassan II University Hospital, Sidi Mohamed Ben Abdellah University, Faculty of Medicine and Pharmacy, Fez , Morocco
³Oral, maxillofacial and ENT surgery department, Hassan II University Hospital, Sidi Mohamed Ben Abdellah University, Faculty of Medicine and Pharmacy, Fez , Morocco
Abstract
Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm primarily originating in the pleura, with the orbit being its most frequent extra-pleural site, often leading to progressive unilateral exophthalmos. Immunohistochemical staining, particularly utilizing y CD34 and STAT6 markers, aids in its diagnosis. Tumors within the SFT spectrum are typically categorized as benign or showing low-grade malignancy; however, prevailing histological features lack prognostic predictive capability. Full surgical resection remains the key prognostic factor. Despite meticulous surgical removal, recurrences and metastases can arise. Surgical excision remains the preferred strategy for recurrent tumors, complemented by limited-efficacy adjunctive treatments. Prolonged and rigorous postoperative monitoring is vital. The rarity of orbital solitary fibrous tumor (OSFT) and its diagnostic challenges underscore the importance of continued research and clinical awareness. This study underscores the value and importance of early intervention and a comprehensive approach in addressing recurrent OSFT, thus augmenting patient outcomes and progressing treatment strategies.
Keywords
Orbit; Solitary fibrous tumor; Recurrence


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