Treatment of Male Infertility Using Some Prostaglandin Synthetase Inhibitors | ||||
Bulletin of Egyptian Society for Physiological Sciences | ||||
Article 2, Volume 28, Issue 1, June 2008, Page 11-16 PDF (187.13 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/besps.2008.36760 | ||||
View on SCiNiTO | ||||
Authors | ||||
Mohamed Ali* 1; M Abdel Mawla2 | ||||
1Medical Biochemistry Department, Faculty of Medicine – Zagazig University | ||||
2Dermatology Department, Faculty of Medicine – Zagazig University | ||||
Abstract | ||||
Indomethacin administration at a dose of 25 mg, three times a day for ninety days to a group (n: 20) of oligospermic men caused an increase in sperm count and motility, a higher level of plasma testosterone and a lower seminal prostaglandin E than the corresponding values before drug intake. The pregnancy rate was 15% (3 out of 20). The present result indicates that indomethacin could be helpful in the treatment of some cases of male infertility. | ||||
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