The Effect of Liver Transplantation Surgery on Anaerobic Gut Microbiota Community and Vitamin B12 levels | ||||
| Alfarama Journal of Basic & Applied Sciences | ||||
| Article 1, Volume 5, Issue 4, October 2024, Page 445-454 PDF (1.49 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ajbas.2024.295010.1215 | ||||
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| Authors | ||||
mohamed Abdel-Raouf abdel-raouf1; Mohamed Abdel-Wahhab1; Ahmed Ismail2; Mohsen El-Sayd Ibrahim2; Taher Abozeid Elsheikh   2; Hisham Mohammad Aldeweik3
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| 1Faculty of Medicine, Mansoura University, Mansoura, Egypt | ||||
| 2Faculty of Science, Port Said University, Port Said, Egypt | ||||
| 3Director of Microbiology Lab., Environmental Monitoring Administration, Ministry of Health, Mansoura, Egypt. | ||||
| Abstract | ||||
| The Anaerobic Gut Microbiota (AGM) is completely associated with human physiology. Compounds like Vitamins, Short Chain Fatty Acids (SCFAs), bile acids, choline metabolites, indole derivatives, polyamines, lipids, neurotransmitters, and neuroactive compounds were linked by the AGM. This study involved 28 Liver transplant (LT) patients from Gastrointestinal Surgery Center (GEC), Faculty of medicine Mansoura University. One hundred and twelve stool and blood samples were taken from all LT patients in the first week before and after the surgery. The results showed that the percentage of anaerobic bacteria isolated from patients before and after one week liver transplantation was (67.18% and 32.82%), respectively. On the other hand, the levels of vitamin B12 (VB-12) in the blood decreased simultaneously with the change of AGM in the first week after surgery compared to the first week before surgery, and this affected the levels of VB12 in the blood of patients with p-value of 0.001. | ||||
| Keywords | ||||
| Liver transplantation; Anaerobic Gut Microbiota; Vitamin B12 | ||||
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