Activation of human oocytes after previously intracytoplasmic sperm injection (ICSI) fertilization failure
Badr, O., Shehata, M., Hassan, E., Gamal Alden, H. (2024). Activation of human oocytes after previously intracytoplasmic sperm injection (ICSI) fertilization failure. EKB Journal Management System, 20(2), 67-78. doi: 10.21608/ajbs.2024.376024
Osama Mohamed Badr; Mohamed Shehata; Eman A. Hassan; Hoda Gamal Alden. "Activation of human oocytes after previously intracytoplasmic sperm injection (ICSI) fertilization failure". EKB Journal Management System, 20, 2, 2024, 67-78. doi: 10.21608/ajbs.2024.376024
Badr, O., Shehata, M., Hassan, E., Gamal Alden, H. (2024). 'Activation of human oocytes after previously intracytoplasmic sperm injection (ICSI) fertilization failure', EKB Journal Management System, 20(2), pp. 67-78. doi: 10.21608/ajbs.2024.376024
Badr, O., Shehata, M., Hassan, E., Gamal Alden, H. Activation of human oocytes after previously intracytoplasmic sperm injection (ICSI) fertilization failure. EKB Journal Management System, 2024; 20(2): 67-78. doi: 10.21608/ajbs.2024.376024

Activation of human oocytes after previously intracytoplasmic sperm injection (ICSI) fertilization failure

African Journal of Biological Sciences
Volume 20, Issue 2, June 2024, Page 67-78  XML PDF (290.57 K)
Document Type: Original Article
DOI: 10.21608/ajbs.2024.376024
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Authors
Osama Mohamed Badr email orcid 1; Mohamed Shehata2; Eman A. Hassan2; Hoda Gamal Alden1
1Animal Biotechnology Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), University of Sadat City (USC)
2International Islamic Center for Population Studies and Research, Al-Azhar University
Abstract
         
          Infertility is a major problem that affects the individual and society. The current investigation aimed to investigate the efficiency of activation with ionomycin or 7% ethanol methods to assist oocyte for improving intracytoplasmic sperm injection (ICSI) outcomes in cases of recurrent failure of ICSI including severe male factor infertility, previous failure of fertilization and implantation. Both methods of assisted oocyte activation (AOA) used in this study recorded highly efficient implications on infertility duration, mature and fertilized oocytes, rates of fertilized, cleavage, blastocyst, embryo grades and pregnancy. It was found that using Ionomycin was preferable more than 7% Ethanol in patients’ treatment with failure fertilization with ICSI.
Keywords
ICSI; AOA; Infertility; Fertilization
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