Evaluation of Serum Cathepsin-S Level in Psoriatic Patients | ||||
| Benha Journal of Applied Sciences | ||||
| Article 2, Volume 9, Issue 8, August 2024, Page 9-12 PDF (418.06 K) | ||||
| Document Type: Original Research Papers | ||||
| DOI: 10.21608/bjas.2024.309034.1469 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Asmaa Mohamed Alrefaie1; Aliaa Elhusseiny Mohammed2; Maha Rashwan3; Dalia Mosaad Moursi  4
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| 1Professor of Dermatology, Venereology and Andrology Faculty of Medicine - Benha University | ||||
| 2Assistant Professor of Dermatology, Venereology and Andrology Faculty of medicine - Benha University | ||||
| 3Lecturer of Clinical Pathology and Hematology Faculty of Medicine - Benha University | ||||
| 4M.B.B.CH. (2014) Faculty of Medicine - Benha University | ||||
| Abstract | ||||
| Background: Psoriasis is a skin condition characterized by the development of raised, red, and scaly plaques over time. Multiple comorbidities, including Crohn's disease, cancer, obesity, and cardiovascular disease, are more common in those with psoriasis. It is well-known that proteases, of which cathepsin S is a part, degrade damaged and undesired proteins. More and more evidence points to its role in a wide range of pathological states and inflammatory disorders. Purpose: The cathepsin-S serum level in psoriasis patients and how it relates to the severity of the illness will be reviewed in this study. Final thoughts: It is possible that serum cathepsin-S is involved in psoriasis. The possible use of cathepsin-S as a biomarker for psoriasis severity is supported by the link between the two.Background: Psoriasis is a skin condition characterized by the development of raised, red, and scaly plaques over time. Multiple comorbidities, including Crohn's disease, cancer, obesity, and cardiovascular disease, are more common in those with psoriasis. It is well-known that proteases, of which cathepsin S is a part, degrade damaged and undesired proteins. More and more evidence points to its role in a wide range of pathological states and inflammatory disorders. Purpose: The cathepsin-S serum level in psoriasis patients and how it relates to the severity of the illness will be reviewed in this study. Final thoughts: It is possible that serum cathepsin-S is involved in psoriasis. The possible use of cathepsin-S as a biomarker for psoriasis severity is supported by the link between the two. | ||||
| Keywords | ||||
| Herpes; simplex virus; cathepsins | ||||
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