Study of the protective role of omega 3 on hepatotoxicity induced by different energy drinks in adult male albino rats | ||||
| Zagazig Journal of Forensic Medicine | ||||
| Article 4, Volume 17, Issue 2 - Serial Number 17, July 2019, Page 46-60 PDF (1.69 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zjfm.2019.12931.1030 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Abla Mohammed Afify; Wesam A Abd Elwhab; Amera A Mohammed; Rehab A Abd Al-Rahman; Samah B El-Sayed 
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| Forensic medicine and clinical toxicolgy. Faculty of medicine for girls Al-Azhar university | ||||
| Abstract | ||||
| Energy drinks (EDs) became a worldwide phenomenon and popular especially among young adult and the liver is one of the most vulnerable organs to toxicity. The aim of this work was to study the sub chronic effect of consumption of different popular energy drinks (power horse (PH) and red bull (RB)) on the liver of adult male albino rats through biochemical and histological parameters. And to determine the possible protective role of Omega-3. Also, to determine the effects of their withdrawal (recovery period). Methodology: Forty-eight adult male albino rats were divided into 8 groups; control, omega 3, RB, PH, each of EDs combined with omega 3 for 4 weeks followed by other 2 weeks as recovery. Blood samples and liver were obtained from the rats for biochemical and histological evaluation. Results: The studied EDs resulted in elevation of the liver function markers (AST, ALT, ALP and total bilirubin) and reduction of total protein with disturbance in the normal histology of the liver. Either treatment with omega 3 or EDs withdrawal improve these changes with better effect to omega 3. Conclusion: EDs are toxic to the liver. omega 3 or EDs withdrawal can ameliorate this toxicity. Recommendation: Strict control of EDs consumption is urgently needed. | ||||
| Keywords | ||||
| energy drinks; power horse; red bull; liver toxicity | ||||
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