Physiological and biochemical effect of α-Amyrin: A review | ||||
| Journal of Medical and Life Science | ||||
| Volume 6, Issue 3, September 2024, Page 443-452 PDF (1.03 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jmals.2024.383360 | ||||
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| Authors | ||||
HAIDAR K.A. ALSAEDI  1; Nawras A. Alwan2; Eman Aboud Al-Masoudi2
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| 1Basrah University, College of Dentistry, Department of Oral Diagnosis, Basrah, Iraq/Department of Basic Science, Faculty of Dentistry, Al-Qadisyah University, Iraq | ||||
| 2Department of Basic Science, Faculty of Dentistry, Al-Qadisyah University, Iraq | ||||
| Abstract | ||||
| Background: Alexander has identified α-Amyrin as a triterpene molecule synthesized from the leaves of this medicinal plant: Celastrus hindsii. A few nations in Southeast Asia as well as Vietnam, and some nations of South America are in require of this specific plant. Both qualitative and quantitative methods have been used in the analysis to give a conclusive affirmance of the existence of α-Amyrin. The included techniques include Gas chromatography-mass spectrometry (GC-MS), Electrospray ionization mass spectrometry (ESI-MS), and Nuclear magnetic resonance (NMR) spectroscopy. It showcases notable inhibition of antioxidants, anti-xanthine oxidase, and anti-tyrosinase, making it an agent that could be employed to treat different illnesses. As far as the biological aspect is concerned, α-amyrin has a multitasking role, primarily it plays the role of an antioxidant, xanthine oxidase inhibitor, and also an agent that could suppress the activity of tyrosinase. Because of all these attributes, it is an exceptionally useful molecule that can be used in developing new drugs targeting various diseases and conditions. Based on the findings it is evident that the relative abundance of a considerable amount of α-amyrin in the leaves of C. hindsii suggests the feasibility of using the plant as a source or extracting and purifying this particular component. | ||||
| Keywords | ||||
| α-Amyrin; anti-inflammatory; mitochondrial | ||||
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