Biochemical Effect of Zolderonic Acid on Experimentally Induced Degeneration of Pancreas | ||||
| Benha Veterinary Medical Journal | ||||
| Article 18, Volume 35, Issue 1, September 2018, Page 171-177 PDF (388.71 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bvmj.2018.38352 | ||||
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| Authors | ||||
| Abdel Maksoud H.A; Omnia M. A.; El-Bialy M. | ||||
| Department of Biochemistry, Faculty of Veterinary Medicine, Benha University | ||||
| Abstract | ||||
| A total number of 160 Wister female rats, 12 -wk. old were taken, weighed and divided into five experimental groups to investigate the effect of streptozotocin (STZ) injection (30 and 60 mg/kg B.W) with and without zoledronic acid (0.15 mg/kg B.W) on some blood serum constituents such as glucose, insulin, calcium, phosphorus and vitamin D. The current results showed that, injection with STZ was associated with a statistically significant elevated in serum glucose, while there was a decrease in serum insulin, calcium and phosphorus. However, zoledronic treatment resulted in a decrease in serum glucose, mean - while it elevate serum insulin, calcium and phosphorus. toward normal Level These results indicated that ZOL acid has beneficial effect on pancreatic biochemical parameters in case of degenerated pancreas. | ||||
| Keywords | ||||
| STZ; Zoledronic acid; pancreas | ||||
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