Biological Effects of Toxoplasma gondii Parasite:1: Ultrastructural Cytological Changes of Hepatocytes Nuclei of The Toxoplasma gondii Me49-Strain-Infected Albino Male Mice
Aref, A., Abdel-Ghaffar, F., Mohamadain, H., Mohamed, E. (2024). Biological Effects of Toxoplasma gondii Parasite:1: Ultrastructural Cytological Changes of Hepatocytes Nuclei of The Toxoplasma gondii Me49-Strain-Infected Albino Male Mice. EKB Journal Management System, 16(2), 123-128. doi: 10.21608/eajbsd.2024.385501
Abdel-Baset M. Aref; Fathy Abdel-Ghaffar; Hoda S. Mohamadain; Esraa Y. Mohamed. "Biological Effects of Toxoplasma gondii Parasite:1: Ultrastructural Cytological Changes of Hepatocytes Nuclei of The Toxoplasma gondii Me49-Strain-Infected Albino Male Mice". EKB Journal Management System, 16, 2, 2024, 123-128. doi: 10.21608/eajbsd.2024.385501
Aref, A., Abdel-Ghaffar, F., Mohamadain, H., Mohamed, E. (2024). 'Biological Effects of Toxoplasma gondii Parasite:1: Ultrastructural Cytological Changes of Hepatocytes Nuclei of The Toxoplasma gondii Me49-Strain-Infected Albino Male Mice', EKB Journal Management System, 16(2), pp. 123-128. doi: 10.21608/eajbsd.2024.385501
Aref, A., Abdel-Ghaffar, F., Mohamadain, H., Mohamed, E. Biological Effects of Toxoplasma gondii Parasite:1: Ultrastructural Cytological Changes of Hepatocytes Nuclei of The Toxoplasma gondii Me49-Strain-Infected Albino Male Mice. EKB Journal Management System, 2024; 16(2): 123-128. doi: 10.21608/eajbsd.2024.385501

Biological Effects of Toxoplasma gondii Parasite:1: Ultrastructural Cytological Changes of Hepatocytes Nuclei of The Toxoplasma gondii Me49-Strain-Infected Albino Male Mice

Egyptian Academic Journal of Biological Sciences, D. Histology & Histochemistry
Volume 16, Issue 2, December 2024, Page 123-128  XML PDF (649.14 K)
Document Type: Original Article
DOI: 10.21608/eajbsd.2024.385501
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Authors
Abdel-Baset M. Aref1; Fathy Abdel-Ghaffar2; Hoda S. Mohamadain3; Esraa Y. Mohamed1
1Cell Biology & Histochemistry Division, Zoology Department, Faculty of Science, South Valley University, Qena, Egypt.
2Parasitology, Zoology Department, Faculty of Science, Cairo University, Egypt.
3Parasitology, Zoology Department, Faculty of Science, South Valley University, Qena, Egypt.
Abstract
Aims: the infection with Toxoplasma gondii parasite causes some dangerous diseases such as the disease toxoplasmosis in the human in the world. Therefore, the present work done to investigate some ultrastructure changes in the nuclei of cells of the liver in Toxoplasma gondii-infected male mice for both 3 months and 5 months. Results: The density of all chromatin types (prefrail, granular and associated nucleolus chromatin and extended chromatin) of nucleus in Toxoplasma gondii infected-mice for both 3 months and 5 months increased versus there control mice and it markedly increased in infected-mice for 5 months versus infected mice 3 months. the number of nucleoli in hepatocytes nucleus markedly increased in control 5 months versus control 3 months and not changed in Toxoplasma gondii infected-mice with time. Conclusion: Toxoplasma gondii Me49 strain-infection has stimulatory effect on the density chromatin distribution in normal hepatocytes nucleus and no effect on the number of nucleoli in hepatocytes nucleus but the age of animal increased the number of nucleoli in normal hepatocytes nucleus.
Keywords
Electron Microscopy - Toxoplasma gondii Me49-Strain; Hepatocyte nucleus; cytology
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