Evaluation of Risk Factors and Outcome of Haemorrhagic Stroke in Neonates | ||||
| Sohag Medical Journal | ||||
| Article 3, Volume 21, Issue 1, January 2017, Page 21-26 PDF (62.47 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/smj.2017.38919 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Abdelrahim Abdrabou Sadek ; Ramadan Ahmed; Nahla Gamal
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| Department of Pediatrics ,Faculty of Medicine, Sohag University, Sohag, Egypt. | ||||
| Abstract | ||||
| Back ground: Few data regarding causes and outcomes of hemorrhagic stroke in late preterm and term neonates are available so we were trying to identify them in this study. Methodes:This prospective case control study was carried out at Sohag University Hospitals, during the period from 1/1/2015 to 31/12/2015 at the department of pediatrics and neonatal care unit at Sohag University. A total of 50 neonates term and late preterm neonates (≥34 weeks gestation) and ≤28 days of life had met the inclusion criteria were 23 males and 27 females. Results: As regard outcome in our study, 8% had grade I, 14 % had grade II, 32% had grade III, 12%had grade IV, 14.5% had subdural hemorrhage and 20% had subarachnoid hemorrhage. So most patients have grade III intracranial hemorrhage and subarachnoid hemorrhage. According to the severity, in our study patients who had mild intracranial hemorrhage represented 48% and patients with moderate intracranial hemorrhage represented 30% and patients with severe intracranial hemorrhage represented 22%. Conclusion: IVH is very rarely reported in full-term and late preterms neonates and may occur in these children with a variety of risk factors, in our study we tried to identify these risk factors and also the outcome and we found that the most frequent associated risk factors were absence of vitamin K administration followed by prolonged labour then neonatal sepsis. | ||||
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| References | ||||
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1- Saver JL, Warach S, Janis S, et al., (2005): Standardizing the structure of stroke clinical andScheel JR, Ray J, Gage FH, et al. Quantitative analysis of gene expression in living adult neural stem cells by gene trapping. Nat Methods.2:363.
2- Takenouchi T, Kasdorf E, Engel M, et al., (2012): Changing pattern of perinatal brain injury in term infants in recent years. PediatrNeurol; 46:106–10.
3- Brouwer AJ, Groenendaal F, Koopman C, et al., (2010): Intracranial hemorrhage in full-termnewborns: a hospital-based cohort study. Neuroradiology 52:567–76.
4- Ou-Yang MC, Huang CB, Huang HC, et al., (2010): Clinical manifestations of symptomaticintracranial hemorrhage in term neonates: 18 years of experience in a medicalcenter. PediatrNeonatol; 51:208–13.
5- Sirgiovanni I, Avignone S, Groppo M, Bassi L, Passera S, Schiavolin P, Lista G, Cinnante C, Triulzi F, Fumagalli M, Mosca F (2014):PediatrRadiol. 44(3):289-96. doi: 10.1007/s00247.
6- Blankenberg FG, Loh NN, Bracci P, et al., (2000):Sonography, CT, and MR imaging: a prospective comparison of neonates with suspected intracranial ischemia and hemorrhage. AJNR 21(1):213-218.
7- Bruno CJ, Beslow LA, Witmer CM, Vossough A, Jordan LC, Zelonis S, Licht DJ, Ichord RN, Smith SE (2014): Hemorrhagic stroke in term and late preterm neonates. Arch Dis Child Fetal Neonatal Ed 99(1):48–53.
8- Afsharkhas L, Khalessi N, KarimiPanah M (2015):Intraventricular hemorrhage in term neonates: sources, severity and outcome. Iran J Child Neurol 9(3):34–39.
9- Towner D, Castro MA, Eby-Wilkens E, Gilbert WM (1999): Effect of mode of delivery in nulliparous women on neonatal intracranial injury. N Engl J Med. 2. 341(23):1709-14.
10- Jhawar BS, Ranger A, Steven DA, Del Maestro RF (2005): A follow-up study of infants with intracranial hemorrhage at full-term. Can J Neurol Sci;32:332-9.
11-Yazidi GA, Srour M, Wintermark P (2014): Risk factors for intraventricularhemorrhage in term asphyxiated newborns treated with hypothermia. PediatrNeurol 50:630–63.
12-Hubbard D, Tobias JD (2006): Intracerebral hemorrhage due to hemorrhagic disease of the newborn and failure to administer vitamin K at birth. South Med J;99:1216-20.
13-Karlowicz MG, White LE(1993): Severe intracranial hemorrhage in a term neonate associated with maternal acetylsalicylic acid ingestion. ClinPediatr (Phila);32:740-3.
14-Gupta SN, Kechli AM, Kanamalla US (2009): Intracranial hemorrhage in term newborns: management and outcomes. Pediatr Neurol. 40(1):1-12.
15- Sandberg DI, Lamberti-Pasculli M, Drake JM, Humphreys RP, Rutka JT (2001): Spontaneous intraparenchymal hemorrhage in full-term neonates. Neurosurgery; 48:1042-8.
16- Sirsi D, Nadiminti L, Packard MA, Engel M, Solomon GE (2007): Apneic seizures: a sign of temporal lobe hemorrhage in full-term neonates. Pediatr Neurol;37:366-70.
17- Fenichel GM (2007): Neonatal hypoxic-ischemic and hemorrhagic cerebral injury. In: Neonatal neurology. 4th ed. Philadelphia: Churchill Livingstone Elsevier, 69-87.
18- Pisani F, Cerminara C, Fusco C, Sisti L (2007): Neonatal status epilepticusvs recurrent neonatal seizures: clinical findings and outcome. Neurology; 69:2177-85. | ||||
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