Expression of ILT 3 in Clonal Lymphoproliferative Disorders
Abo- El Wafa, H., Aziz, S., Ahmed, H., Sayed, S., El-Gawad, A., Saber, D. (2017). Expression of ILT 3 in Clonal Lymphoproliferative Disorders. EKB Journal Management System, 21(3), 211-207. doi: 10.21608/smj.2017.39611
Hasnaa Ahmed Abo- El Wafa; Shereen. philip Aziz; Heba Abdul Hafez Ahmed; Sherif Abdel Aziz Sayed; AbdElhady RagabAbd El-Gawad; Doaa Elsayed Saber. "Expression of ILT 3 in Clonal Lymphoproliferative Disorders". EKB Journal Management System, 21, 3, 2017, 211-207. doi: 10.21608/smj.2017.39611
Abo- El Wafa, H., Aziz, S., Ahmed, H., Sayed, S., El-Gawad, A., Saber, D. (2017). 'Expression of ILT 3 in Clonal Lymphoproliferative Disorders', EKB Journal Management System, 21(3), pp. 211-207. doi: 10.21608/smj.2017.39611
Abo- El Wafa, H., Aziz, S., Ahmed, H., Sayed, S., El-Gawad, A., Saber, D. Expression of ILT 3 in Clonal Lymphoproliferative Disorders. EKB Journal Management System, 2017; 21(3): 211-207. doi: 10.21608/smj.2017.39611

Expression of ILT 3 in Clonal Lymphoproliferative Disorders

Sohag Medical Journal
Article 24, Volume 21, Issue 3, October 2017, Page 211-207  XML PDF (43.9 K)
Document Type: Original Article
DOI: 10.21608/smj.2017.39611
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Authors
Hasnaa Ahmed Abo- El Wafa1; Shereen. philip Aziz2; Heba Abdul Hafez Ahmed3; Sherif Abdel Aziz Sayed1; AbdElhady RagabAbd El-Gawad4; Doaa Elsayed Saber4
1Department of Clinical Pathology,Faculty of Medicine, Sohag University.
2Department of Clinical and Pathology,sohag faculty of medicine,sohag university
3Department of Clinical Pathology and Chemistry, Sohag Faculty of Medicine, Sohag University
4Department of Clinical and Chemical Pathology, Faculty of Medicine, Sohag University
Abstract
B-cell chronic lymphocytic leukemia (B-CLL), also known as chronic lymphoid leukemia (CLL), is the most common type of leukemia (a type of cancer of the white blood cells) in adults, CLL affects B cell lymphocytes,Immunoglobulin-like transcript-3 (ILT-3), a member of the immunoglobulin superfamily, is a transmembrane inhibitory receptor expressed on antigen-presenting cells (APCs) such as monocytes and dendritic cells (DCs) as well as on endothelial  cells The aims of this study was to evaluate the expression of  ILT-3 in acute and chronic leukamias and its relation to other diagnostic markers and if it has a role in leukamiogenesis A total of 5 papers were obtained using the mentioned keywords in the research of all internet-based databases
Patients and Methods: Case control study, included 30 patients 15 patients with CLLand 15patients no detectable disease recruited from Sohag university hospital and the mean age of each of them was 32.8 years.   There are different method of detection of IL3 in different studies such as PCR, ELISA and (FCM).
Results: The frequency of ILT3 positive CLL B cells was higher in patients with lymphoid tissue involvement, suggesting that ILT3 may have prognostic value in CLL
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