Ultrasound Guided Platelet Rich Plasma Injection in Patients with Primary Knee Osteoarthritis
El-Deeb, A., EL-Barbary, A., El Khouly, R., Elfeky, N. (2019). Ultrasound Guided Platelet Rich Plasma Injection in Patients with Primary Knee Osteoarthritis. EKB Journal Management System, 76(3), 3633-3640. doi: 10.21608/ejhm.2019.39900
Ali Eed El-Deeb; Amal Mohamad EL-Barbary; Radwa Mostafa El Khouly; Nevien Ibrahim Elfeky. "Ultrasound Guided Platelet Rich Plasma Injection in Patients with Primary Knee Osteoarthritis". EKB Journal Management System, 76, 3, 2019, 3633-3640. doi: 10.21608/ejhm.2019.39900
El-Deeb, A., EL-Barbary, A., El Khouly, R., Elfeky, N. (2019). 'Ultrasound Guided Platelet Rich Plasma Injection in Patients with Primary Knee Osteoarthritis', EKB Journal Management System, 76(3), pp. 3633-3640. doi: 10.21608/ejhm.2019.39900
El-Deeb, A., EL-Barbary, A., El Khouly, R., Elfeky, N. Ultrasound Guided Platelet Rich Plasma Injection in Patients with Primary Knee Osteoarthritis. EKB Journal Management System, 2019; 76(3): 3633-3640. doi: 10.21608/ejhm.2019.39900

Ultrasound Guided Platelet Rich Plasma Injection in Patients with Primary Knee Osteoarthritis

The Egyptian Journal of Hospital Medicine
Article 3, Volume 76, Issue 3, July 2019, Page 3633-3640  XML PDF (617.9 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2019.39900
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Authors
Ali Eed El-Deeb; Amal Mohamad EL-Barbary; Radwa Mostafa El Khouly; Nevien Ibrahim Elfeky email
Department of Rheumatology and Rehabilitation, Faculty of Medicine, Tanta University
Abstract
Background: Osteoarthritis is a leading cause of pain, disability, and socioeconomic cost worldwide and the knee is one of the most commonly affected joint. Objective: to evaluate clinical and functional therapeutic effect of ultrasound guided intraarticular or periarticular platelet rich plasma (PRP) injection in treatment of patients with primary knee osteoarthritis. Patients and Methods: eighty patients with primary knee osteoarthritis were divided into two groups: Group I: 50 knees, group II: 30 knees. Both groups were treated by PRP injection into the lateral recess of the knee group I or into painful periarticular structure that have previously been identified on ultrasound group II. Results: The VAS in group I (6.3±1.45) and II (6.57±1.30) significantly improved after injection (1.30±0.97 and 1.43±0.77; p<0.001). The range of movement (ROM) (flexion) significantly improved in both groups after injection. The WOMAC significantly improved in both groups after injection (p<0.001); (group I: 14.04±7.73 vs group II: 15.20±7.12). The KOOS score significantly improved in group I (41.93±11.05 to 75.43±7.70; p<0.001) and group II (39.83±12.46 to 76.08± 7.12; p<0.001) after injection. There was a significant improvement in the percentage of different parameters in mild and moderate knee osteoarthritis in both groups. Conclusion: Ultrasound guided single dose PRP injection is a safe and effective method for treating all grades of knee OA mainly mild to moderate also injection in periarticular pain generator structures reduce pain and improve knee function.
Keywords
knee; osteoarthritis; Ultrasound-guided injection; platelet rich plasma
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