Severe Bleeding in Preoperative Conditions: Emergent Interventions to Control Condition-An Updated Review

Al Salman, Laila Hassan; Al-Zaaqi, Abdul Aziz Khaled; Almannaa, Sultan Ibrahim Ahmed; Alneami, Salhah Yahya; Awaji, Yahya Mahdi Abdullah; Ebani, Emad Souleman; Alharthi, Alanoud; Altamimi, Ghadah; Al Sahhaf, Nada Emad; Almuabbadi, Basel Hamid; Alanazi, Hazzaa; Albishi, Reem N; Alaryani, Shatha Ahmed; Alhejali, Nada Ahmad; Algarni, Maryam Salem; Hekoomi, Khulood Abdu; Jafri, Maha Mohammed; Samtah, Zohoor Mahamaud; Bin Nafesah, Haifa Abdulaziz; Alanazi, Shadia Maashi

doi:10.21608/ejchem.2024.346876.11031

Al Salman, L., Al-Zaaqi, A., Almannaa, S., Alneami, S., Awaji, Y., Ebani, E., Alharthi, A., Altamimi, G., Al Sahhaf, N., Almuabbadi, B., Alanazi, H., Albishi, R., Alaryani, S., Alhejali, N., Algarni, M., Hekoomi, K., Jafri, M., Samtah, Z., Bin Nafesah, H., Alanazi, S. (2024). Severe Bleeding in Preoperative Conditions: Emergent Interventions to Control Condition-An Updated Review. EKB Journal Management System, 67(13), 1803-1811. doi: 10.21608/ejchem.2024.346876.11031

Laila Hassan Al Salman; Abdul Aziz Khaled Al-Zaaqi; Sultan Ibrahim Ahmed Almannaa; Salhah Yahya Alneami; Yahya Mahdi Abdullah Awaji; Emad Souleman Ebani; Alanoud Alharthi; Ghadah Altamimi; Nada Emad Al Sahhaf; Basel Hamid Almuabbadi; Hazzaa Alanazi; Reem N Albishi; Shatha Ahmed Alaryani; Nada Ahmad Alhejali; Maryam Salem Algarni; Khulood Abdu Hekoomi; Maha Mohammed Jafri; Zohoor Mahamaud Samtah; Haifa Abdulaziz Bin Nafesah; Shadia Maashi Alanazi. "Severe Bleeding in Preoperative Conditions: Emergent Interventions to Control Condition-An Updated Review". EKB Journal Management System, 67, 13, 2024, 1803-1811. doi: 10.21608/ejchem.2024.346876.11031

Al Salman, L., Al-Zaaqi, A., Almannaa, S., Alneami, S., Awaji, Y., Ebani, E., Alharthi, A., Altamimi, G., Al Sahhaf, N., Almuabbadi, B., Alanazi, H., Albishi, R., Alaryani, S., Alhejali, N., Algarni, M., Hekoomi, K., Jafri, M., Samtah, Z., Bin Nafesah, H., Alanazi, S. (2024). 'Severe Bleeding in Preoperative Conditions: Emergent Interventions to Control Condition-An Updated Review', EKB Journal Management System, 67(13), pp. 1803-1811. doi: 10.21608/ejchem.2024.346876.11031

Al Salman, L., Al-Zaaqi, A., Almannaa, S., Alneami, S., Awaji, Y., Ebani, E., Alharthi, A., Altamimi, G., Al Sahhaf, N., Almuabbadi, B., Alanazi, H., Albishi, R., Alaryani, S., Alhejali, N., Algarni, M., Hekoomi, K., Jafri, M., Samtah, Z., Bin Nafesah, H., Alanazi, S. Severe Bleeding in Preoperative Conditions: Emergent Interventions to Control Condition-An Updated Review. EKB Journal Management System, 2024; 67(13): 1803-1811. doi: 10.21608/ejchem.2024.346876.11031

	Severe Bleeding in Preoperative Conditions: Emergent Interventions to Control Condition-An Updated Review
Egyptian Journal of Chemistry
Volume 67, Issue 13, December 2024, Page 1803-1811 PDF (473.56 K)
Document Type: Review Articles
DOI: 10.21608/ejchem.2024.346876.11031
View on SCiNiTO
Authors
Laila Hassan Al Salman¹; Abdul Aziz Khaled Al-Zaaqi²; Sultan Ibrahim Ahmed Almannaa²; Salhah Yahya Alneami²; Yahya Mahdi Abdullah Awaji²; Emad Souleman Ebani²; Alanoud Alharthi²; Ghadah Altamimi²; Nada Emad Al Sahhaf²; Basel Hamid Almuabbadi²; Hazzaa Alanazi²; Reem N Albishi²; Shatha Ahmed Alaryani²; Nada Ahmad Alhejali²; Maryam Salem Algarni²; Khulood Abdu Hekoomi²; Maha Mohammed Jafri²; Zohoor Mahamaud Samtah²; Haifa Abdulaziz Bin Nafesah²; Shadia Maashi Alanazi²
¹First Riyadh Health Cluster, Ministry of Health, Saudi Arabia
²King Saud Medical City, Saudi Arabia
Abstract
Background: Severe bleeding during preoperative and intraoperative conditions remains a major cause of morbidity and mortality. The risk of hemorrhage is heightened by factors such as trauma, anticoagulant therapies, and surgical complications. Effective preoperative management and timely interventions are crucial for controlling severe blood loss and minimizing the associated risks. Aim: This review aims to provide an updated synthesis of interventions and strategies used to control severe bleeding in preoperative conditions, focusing on the mechanisms of hemorrhage, risk factors, and the management techniques employed to stabilize patients. Methods: A comprehensive review of the existing literature was conducted, analyzing the underlying mechanisms of bleeding, including coagulopathy and the body's response to hemorrhagic shock. Clinical approaches such as fluid resuscitation, pharmaceutical interventions, and surgical techniques for managing severe bleeding were discussed. Results: The review highlighted that hemorrhagic shock often occurs due to trauma-induced coagulopathy, shock, or the consumption of clotting factors. Fluid resuscitation strategies, including the use of crystalloids, colloids, and blood products, are essential in stabilizing patients. Additionally, medications such as inotropes and adrenergic agonists play a vital role in improving cardiac output and blood pressure. Effective interventions in managing hemorrhagic shock were found to rely heavily on rapid response, tailored treatments, and evidence-based guidelines. Conclusion: Severe bleeding in preoperative conditions presents a complex challenge. Immediate intervention through appropriate fluid therapy, the use of pharmaceuticals, and surgical techniques are essential in controlling blood loss. The timely recognition and management of coagulopathy, hemorrhagic shock, and underlying health conditions are critical to improving patient outcomes and reducing mortality in these high-risk situations.
Keywords
severe bleeding; hemorrhagic shock; fluid resuscitation; anticoagulants; coagulopathy; trauma; surgical intervention


Statistics Article View: 148 PDF Download: 123