CLINICAL COMPARISON OF TOPICAL APPLICATION OF CURCUMIN GEL VERSUS GELATIN SPONGE IN PAIN MANAGEMENT AND WOUND HEALING AFTER FREE GINGIVAL GRAFT HARVESTING: A RANDOMIZED CONTROLLED CLINICAL TRIAL. | ||||
| Egyptian Dental Journal | ||||
| Volume 71, Issue 1 - Serial Number 3, January 2025, Page 291-302 PDF (1.78 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/edj.2024.327680.3228 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Tansim Khaled   1; Manal Mohamed Hosny 2; Mohamed Atef 3
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| 1B.D.Sc (2017), Cairo University | ||||
| 2Professor of Oral medicine and Periodontology, Faculty of Dentistry, Cairo University | ||||
| 3Lecturer of Periodontology, Faculty of Dentistry, Cairo University | ||||
| Abstract | ||||
| Objectives: The aim of this study was to compare the effect of using 2% curcumin gel versus gelatin sponge when applied as wound dressing to palatal donor site on pain perception and wound healing after epithelialized gingival graft (EGG) harvesting. Methodology: The present study included 30 patients with mucogingival defects that can be treated by application of EGG. The patients were allocated to 2 groups, an intervention group and control group. The palatal donor site received a hemostatic gelatin sponge and 2% curcumin gel in the control and intervention groups respectively after EGGs harvesting from the palate. Patients were observed for 4 weeks, evaluating the pain level by using the visual analogue scale and the consumption of analgesic during the first postoperative week. Soft tissue healing and re-epithelialization of the palatal wound were evaluated for 4 weeks post-surgery. Results: There was significant difference between both groups in pain scores assessed from the 3rd to the 7th days after surgery. The number of analgesic tablets taken by the patients in the control group was significantly higher than that of the intervention from the on 3rd day and 4th days. On the second week wound healing, scores measured in the intervention group were significantly higher than the control group (p=0.035). For wound re-epithelialization for all intervals, there was no significant difference between groups (p>0.05). Conclusions: Curcumin gel represents a useful palatal wound dressing material that has features that enhances palatal wound re-epithelization, healing and can reduce post-operative pain. . | ||||
| Keywords | ||||
| Pain management; Autogenous soft tissue graft; Wound healing | ||||
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