Eco-friendly and superficial approach for synthesis of silver nanoparticles using aqueous extract of and L seeds for evaluation of their antibacterial, antiviral, and anticancer activities a focus study on its impact on seed germination and seedling growth of and
Mahfouz, A., Daigham, G., Radwan, A., Mohamed, A. (2020). Eco-friendly and superficial approach for synthesis of silver nanoparticles using aqueous extract of and L seeds for evaluation of their antibacterial, antiviral, and anticancer activities a focus study on its impact on seed germination and seedling growth of and. EKB Journal Management System, 19(4), 401-413. doi: 10.4103/epj.epj_48_20
Amira Y. Mahfouz; Ghadir E. Daigham; Asmaa M. Radwan; Abeer A. Mohamed. "Eco-friendly and superficial approach for synthesis of silver nanoparticles using aqueous extract of and L seeds for evaluation of their antibacterial, antiviral, and anticancer activities a focus study on its impact on seed germination and seedling growth of and". EKB Journal Management System, 19, 4, 2020, 401-413. doi: 10.4103/epj.epj_48_20
Mahfouz, A., Daigham, G., Radwan, A., Mohamed, A. (2020). 'Eco-friendly and superficial approach for synthesis of silver nanoparticles using aqueous extract of and L seeds for evaluation of their antibacterial, antiviral, and anticancer activities a focus study on its impact on seed germination and seedling growth of and', EKB Journal Management System, 19(4), pp. 401-413. doi: 10.4103/epj.epj_48_20
Mahfouz, A., Daigham, G., Radwan, A., Mohamed, A. Eco-friendly and superficial approach for synthesis of silver nanoparticles using aqueous extract of and L seeds for evaluation of their antibacterial, antiviral, and anticancer activities a focus study on its impact on seed germination and seedling growth of and. EKB Journal Management System, 2020; 19(4): 401-413. doi: 10.4103/epj.epj_48_20

Eco-friendly and superficial approach for synthesis of silver nanoparticles using aqueous extract of and L seeds for evaluation of their antibacterial, antiviral, and anticancer activities a focus study on its impact on seed germination and seedling growth of and

Egyptian Pharmaceutical Journal
Volume 19, Issue 4, October 2020, Page 401-413  XML PDF (4.31 MB)
DOI: 10.4103/epj.epj_48_20
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Authors
Amira Y. Mahfouz; Ghadir E. Daigham; Asmaa M. Radwan; Abeer A. Mohamed
Abstract
Background
Silver nanoparticles (AgNPs) have fascinated extensive interest owing to their potential applications, especially in biomedicine.
Materials and methods
Through this investigation, AgNPs were green synthesized from AgNO using and aqueous seed extracts as a reducing agent. Biosynthesized AgNPs were characterized using transmission electron microscopy, Fourier-transform infrared spectroscopy, zeta potential, and dynamic light scattering. Antibacterial, antiviral, and anticancer activities of AgNPs were studied. Furthermore, the effect of biosynthesized AgNPs on seed germination and seedling growth of and was determined.
Results and conclusion
Results evoked the ability of and aqueous seed extracts to build up AgNPs in spherical shape with average size of 20 and 50 nm, respectively, by using transmission electron microscopy analysis. The results indicate the ability of and AgNPs to inhibit both tested gram-positive and gram-negative bacteria. It is conceivable from the results that AgNPs of the are markedly effective against herpes simplex virus-1 in terms of decreased viral load and mortality, exhibiting 83.23 and 94.54% of antiviral activity, respectively. Furthermore, in-vitro studies of and AgNPs against hepatocellular carcinoma have shown good cytotoxic effect, with IC50 values equal to 7.12 and 4.98 µg/ml, respectively. AgNPs exert a promoting action on seed germination percentage and seedling growth of both and . This study indicated an economical, simple, and efficient ecofriendly technique using aqueous seed extracts of and for synthesis of AgNPs and confirmed that green AgNPs are safer.
Keywords
AgNPs; anticancer and seed germination; Antiviral; L
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