REVOLUTIONIZING HEALTHCARE: UNVEILING THE POWER OF REGENERATIVE MEDICINE AND TISSUE ENGINEERING | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Volume 48, Issue 1, June 2025, Page 59-72 PDF (687.54 K) | ||||
| Document Type: Review Article | ||||
| DOI: 10.21608/bfsa.2025.331318.2328 | ||||
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| Authors | ||||
Ritesh Bhole1; Harshad Kapare2; Pawan Karwa  3; Sonali Labhade4
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| 1Department of pharmaceutical chemistry,1Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Sant Tukaram Nagar, Pimpri, Pune-411018,India | ||||
| 2Department of Pharmaceutics,Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Sant Tukaram Nagar, Pimpri, Pune-411018,India | ||||
| 3Depart of pharmacology,Dr D Y Patil Institute of Pharmaceutical sciences and research pimpri,Pune | ||||
| 4Department of pharmaceutical chemistry,Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Sant Tukaram Nagar, Pimpri, Pune-411018,India | ||||
| Abstract | ||||
| This comprehensive review explores the integration of stem cell therapies and tissue engineering, driving advancements as a new regenerative medicine approach. It discusses diverse applications across various tissues, including bone, cartilage, heart, skin, neural, liver, ocular, muscle, and renal tissues. Successful outcomes, such as bone fracture management, cardiac tissue regeneration, and spinal cord injury repair, are highlighted through compelling case studies. The review emphasizes challenges like immune rejection risks and regulatory complexities in translating these techniques to clinical practice. It also underscores the use of biomolecules, growth factors, and controlled release strategies to guide tissue maturation. Collaboration among researchers, clinicians, and regulatory agencies is crucial, and personalized medicine offers promise for individualized treatment. Emerging trends, like organoids and organ-on-a-chip technologies, are reshaping the field, potentially reducing reliance on donor organs. Regulatory considerations, interdisciplinary collaboration, and innovative technologies converge to unlock regenerative medicine's transformative potential for biomedical research and patient care. | ||||
| Keywords | ||||
| Biomedical Innovation; biomolecules; controlled release; organoids; organ-on-a-chip | ||||
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