Pattern of chronic urticaria in SohagUniversity Hospitals | ||||
| Sohag Medical Journal | ||||
| Article 14, Volume 21, Issue 2, July 2017, Page 125-131 PDF (100.57 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/smj.2017.41241 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Reham Ezz El-Dawla El Sharkawy1; Wafaa Mohamed Abd El- Maged2; Doaa Ahmed3; Sahar AbdElwahed4 | ||||
| 1Departments of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University. | ||||
| 2Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University. | ||||
| 3Departement of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University. | ||||
| 4Departement of Clinical Pathology, Faculty of Medicine, Sohag University. | ||||
| Abstract | ||||
| Background:Chronic urticaria (CU) is a skin disorder characterized by the recurrent appearance of wheals and/or angioedema for at least 6 weeks. CU is a heterogeneous disorder which includes chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIU). Objective:To study the pattern of chronic urticaria among the patients attending dermatology outpatient clinic in Sohag University Hospitals and to study the association between the results of autologous serum skin test (ASST) and urticaria severity score (USS)and to detect serum level of anti IgE receptors antibodies using ELISA. Results:ASST was positive in 41 (38 %) patients andthere was a statistically significant relation between ASST result and duration of the disease (p value 0.014).22 (20.4%) of the patients had mild score , 50 (46.3%) had moderate score and 36 (33.3%) had severe score. The relation of USS to the positivity of ASST was statistically significant (p value 0.000).The mean of anti IgE receptor antibodies in ASST positive group was more than that of those negative ones that was highly statistically significant ( P value 0.000). Conclusion:ASST remains a baseline diagnostic test for CAU. Patients with CAU had more frequent attacks and longer duration than other types of chronic urticaria. | ||||
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1.Ferrer M. and Kaplan AP. Progress and Challenges in the Understanding of Chronic Urticaria. Allergy, Asthma, and Clinical Immunology 2007; 3 (1): 31–35.
2.Losol P., Yoo HS. and Park HM. Molecular Genetic Mechanisms of Chronic Urticaria. Allergy, Asthma & Immunology Research 2014 ;6 (1) :13-21.
3.Bernstein JA., Lang DM.and Khan DA. The diagnosis and management of acute and chronic urticaria: 2014 update. Journal of Allergy and Clinical Immunology.2014; 133: 1270-1277.
4.Maurer M., Bindslev- Jensen C., Gimenez-Arnau A., Godse K., Grattan C.E.M., Hide M. and Kaplan A.P. Chronic idiopathic urticaria (CIU) is no longer idiopathic: time for an update. British Association of Dermatologists 2013;168 (2) :455-456.
5.Khan DA. Chronic urticaria: Diagnosis and management . Allergy Asthma 2008; 29: 439 –446.
6.Saini S.S..Chronic Spontaneous Urticaria Etiology and Pathogenesis.Immunology and allergy clinics of North America. 2014; 34 : 33–52.
7. Weller K., Maurer M. Grattan C., Nakonechna A., Arnau MA. andFrutos JO . ASSURE-CSU: a real-world study of burden of disease in patients with symptomatic chronic spontaneous urticaria. Clinical and Translational Allergy 2015; 5:29.
8.Kaplan AP. Treatment of Chronic Spontaneous Urticaria. Allergy, Asthma & Immunology Research 2012 ;4 (6) :326-331.
9.Mlyneka A., Maurerb M., and Zalewska A. Update on chronic urticaria: focusing on mechanisms. Current Opinion in Allergy and Clinical Immunology 2008, 8:433–437.
10.Criado PR., Criado RF., Maruta CW. and Silva VM. Chronic urticaria in adults: state-of-the-art in the new millennium. An Bras Dermatol. 2015; 90 (1): 74-89.
11.Greaves MW. Chronic idiopathic urticaria. Current Opinion in Allergy and Clinical Immunology 2003; 3 (5) :363-8.
12.Kanani A., Schellenberg R. and Warrington R. Urticaria and angioedema. Allergy, Asthma & Clinical Immunology 2011; 7 (1) : S9.
13.Al-Hamamy HR., Hameed AF.andAbdulhadi AS. Autologous Serum Skin Test as a Diagnostic Aid in Chronic Idiopathic Urticaria.ISRN Dermatology 2013.
14.Ben-Shoshan M. ,Blinderman I. andRaz A. Psychosocial factors and chronic spontaneous urticaria: asystematic review. European Journal of allergy and Clinical Immunology 2013; 68: 131–141.
15.Sanchez-Borges M., Asero R., Ansotegui IJ., Baiardini I., Bernstein JA., Walter Canonica G., Gower R., and Kahn DA. Diagnosis and Treatment of Urticaria and Angioedema: A Worldwide Perspective. World Allergy Organization 2012; 5:125–147.
16.George M., Balachandran C., Prabhu S. Chronic idiopathic urticaria: comparison of clinical features with positive autologous serum skin test. Indian journal of dermatology 2008;74 (2) :105-8.
17.Al-Ahmad M., Alowayesh MS. And Carroll NV.Economic burden of refractory chronic spontaneous urticaria on Kuwait’s health system.Clinicoecon Outcomes Res. 2016; 8: 163–169.
18.Inamadar AC. And Palit A. Management of autoimmune urticaria. Indian Journal of Dermatology, Venereology and Leprology 2008; 74 (2): 89–91.
19.Lapi F., Cassano N., Pegoraro V., Cataldo N., Heiman F., Cricelli I., Levi M., Colombo D., Zagni E., Cricelli C. and Vena GA.Epidemiology of chronic spontaneous urticaria: results from anationwide, population-based study in Italy.British Journal of Dermatology 2016; 174 (5) : 996-1004.
20.Heng JK., KohLJ., Paul ST. and Wee DCA.A study of treatment adherence and quality of life among adults with chronic urticaria in Singapore.Asia Pac Allergy 2015; 5 (4) : 197–202 .
21.Ue AP., Souza PK., Rotta O., Furlani WJ. , Lima AR. and Sabbag DS. Quality of life assessment in patients with chronic urticaria. Journal Brazilian Annals of Dermatology 2011; 86 (5) :897-904..
22.Vichayanond P, Sunthornchart S, Singhivannusorn V. Prevalence of asthma, allergic rhinitis and eczema among university students in Bangkok. Resp Medicine 2002; 96: 34–38.
23.Yadav MK., Rishi JP., Nijawan S. Chronic urticaria and Helicobacter pylori. Indian Journal of Medical Sciences 2008; 62:157-62.
24.Moreiraa A., Rodriguesa J., Delgadoa L., Fonsecaa J. andVaza M. Is Helicobacter pylori infection associated with chronic idiopathic urticaria?.Allergologia et Immunopathologia 2003;31 (4) :209-14.
25.Confino-Cohen R. , Chodick G., Shalev V., Leshno M., Kimhi O. and Goldberg A. Chronic urticaria and autoimmunity: Associations found in alarge population study. Journal of Allergy Clinical Immunology 2012; 129: 1307-13.
26.Kulthanan K., Jiamton S., Thumpimukvatana N. and Pinkaew S. Chronic idiopathic urticaria: prevalence and clinical course. International Journal of Dermatology 2007 ;34 (5) :294-301.
27.Sussman G., Hebert J. , Gulliver W., Lynde C., Waserman S., Kanani A., Ben-Shoshan M. and Horemans S. Insights and advances in chronic urticaria: a Canadian perspective. Allergy, Asthma and Clinical Immunology 2015; 11:7.
28.ToubiE., KesselA., AvshovichN. , BambergerE., SaboE., Nusem D. and Panasoff J.Clinical and laboratory parameters in predicting chronic urticaria duration: a prospective study of 139 patients.Allergy 2004: 59: 869–873.
29.Asero R., Tedeschi A., Lorini M., Salimbeni R., Zanoletti T. and Miadonna A.Chronic urticaria: novel clinical and serological aspects. ClinExp Allergy. 2001; 31 (7) :1105-10.
30.Nettis E, Dambra P, D’Oronzio L, Cavallo E, Loria MP, Fanelli M, et al. Reactivity to autologous serum skin test and clinical features in chronic idiopathic urticaria. Journal of Clinical & Experimental Dermatology Research 2002; 27: 29‑31.
31.Caproni M, Volpi W, Giomi B, Cardinali C, Antiga E, Melani L. Chronic idiopathic and chronic autoimmune urticaria: Clinical and immunopathological features of 68 subjects. ActaDermato-Venereologica 2004; 84: 288 - 290.
32.Sabroe R.A., Poon E., Orchard GE., Lane D., Francis DM., Barr RM., Black MM., Black AK., and Greaves MW. Cutaneous inflammatory cell infiltrate in chronic idiopathic urticaria: Comparison of patients with and without anti-FceRI or anti-IgE autoantibodies. Journal of Allergy and Clinical Immunology 1999; 103(3):484-493.
33.Kessel A., Helou W., Bamberger E., Sabo E., Nusem D., Panassof J. and Toubi E.Elevated serum total IgE--a potential marker for severe chronic urticaria.International Archives of Allergy and Immunology 2010; 153 (3) :288-93. | ||||
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