Incidence of malignancy of nasopharyngeal swellings in adults
Abed elrahman, M. (2017). Incidence of malignancy of nasopharyngeal swellings in adults. EKB Journal Management System, 21(3), 393-398. doi: 10.21608/smj.2017.41246
Mahmoud Sayed Abed elrahman. "Incidence of malignancy of nasopharyngeal swellings in adults". EKB Journal Management System, 21, 3, 2017, 393-398. doi: 10.21608/smj.2017.41246
Abed elrahman, M. (2017). 'Incidence of malignancy of nasopharyngeal swellings in adults', EKB Journal Management System, 21(3), pp. 393-398. doi: 10.21608/smj.2017.41246
Abed elrahman, M. Incidence of malignancy of nasopharyngeal swellings in adults. EKB Journal Management System, 2017; 21(3): 393-398. doi: 10.21608/smj.2017.41246

Incidence of malignancy of nasopharyngeal swellings in adults

Sohag Medical Journal
Article 45, Volume 21, Issue 3, October 2017, Page 393-398  XML PDF (245.07 K)
Document Type: Original Article
DOI: 10.21608/smj.2017.41246
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Author
Mahmoud Sayed Abed elrahman
Department of ENT, Faculty of Medicine, Sohag University
Abstract
Introduction: Nasopharyngeal mass resembles a confounding problem in adults because of the increased fearof malignancy with age advancement. Histopathological pattern of nasopharyngeal lesions varies from commonbenign lesions such as hyperplastic lymphoid tissue and benign nasopharyngeal cysts to malignant diseases suchas lymphoma and nasopharyngeal carcinoma.
Methods: This prospective study included all patients underwent a nasopharyngeal biopsy for a nasopharyngealmass in 2 years period from June 2014 to June 2016. Blind biopsy was taken for cases clinically suspiciousfor having nasopharyngeal carcinoma. Patients histopathological findings were analyzed as regard demographic
data and clinical presentation.
Results: A total of 100 patients (54 males and 46 females) were included.Patient age ranged between 18 and 76 years (mean 39.37 years, SD 1.628). The most commonly detectedpathological lesion was hyperplastic lymphoid tissue hyperplasia (59%). Malignant lesions constituted 39% ofthe study population (10% squamous cell carcinoma, 14% undifferentiated carcinoma and 15% malignantlymphoma). In addition, benign nasopharyngeal cysts were diagnosed in 2 % of cases.
Conclusion: Benign lesions are more commonly detected in the nasopharynx in adult population particularlyhyperplastic lymphoid tissue. Histopathological examination ofnasopharyngeal mass is very essential to roll outmalignancy which is not uncommon.
Keywords
nasopharyngeal; Lymphoid hyperplasia; carcinoma; Lymphoma; histopathology
Supplementary Files
References
  1. Kamel RH, Ishak EA (1990) Enlarged adenoid and adenoidectomy in adults: Endoscopic approach and histopathological study. J LaryngolOtol 104: 965-967.
  2. Hopping SB, Keller JD, Goodman ML, Montgomery WW (1983)  Nasopharyngeal masses in adults. Ann OtolRhinolLaryngol 92: 137-140.
  3. Wang WH, Lin YC, Weng HH, Lee KF (2011) Narrow-band imaging for diagnosing adenoid hypertrophy in adults: A simplified grading and histologic correlation. Laryngoscope 121: 965-970.
  4. Mattila PS, Tarkkanen J (1997) Age-associated changes in the cellular composition of the human adenoid. Scand J Immunol 45: 423-427.
  5. Chang ET, Adami HO (2006) The enigmatic epidemiology of nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Pre 15: 1765-1777.
  6. Sekiya K, Watanabe M, Nadgir RN, Buch K, Flower EN, et al. (2014)  Nasopharyngeal cystic lesions: Tornwaldt and mucous retention cysts of the nasopharynx: Findings on MR imaging. J Comput Assist Tomogr 38: 9-13.
  7. Abu-Ghanem S, Carmel NN, Horowitz G, Yehuda M, Leshno M, et al.  (2015) Nasopharyngeal biopsy in adults: A large-scale study in a non endemic area. Rhinology 53: 142-148.
  8. Biswas G, Ghosh SK, Mukhopadhyay S, Bora H (2002) A clinical study of nasopharyngeal masses. Indian J Otolaryngol Head Neck Surg 54: 193-195.
  9. Berkiten G, Kumral TL, Yildirim G, Uyar Y, Atar Y, et al. (2014) Eight years of clinical findings and biopsy results of nasopharyngeal pathologies in 1647 adult patients: A retrospective study. B-ENT 10: 279-284.
  10. Brodsky L, Koch RJ (1993) Bacteriology and immunology of normal and diseased adenoids in children. Arch Otolaryngol Head Neck Surg 119: 821-829.
  11. Yildirim N, Sahan M, Karslioğlu Y (2008) Adenoid hypertrophy in adults: Clinical and morphological characteristics. J Int Med Res 36: 157-162.
  12. Glynn F, Keogh IJ, Ali TA, Timon CI, Donnelly M (2006) Routine nasopharyngeal biopsy in adults presenting with isolated serous otitis media: Is it justified? J LaryngolOtol 120: 439-441.
  13. Johannsson J, Sveinsson T, Agnarsson BA, Skaftason S (1997) Malignantnasopharyngeal tumours in Iceland. ActaOncol 36: 291-294.
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