Attenuating the hormonal response to rigid bronchoscopy; comparison between iv fentanyl, dexmedetomidine or lidocaine | ||||
| Sohag Medical Journal | ||||
| Article 22, Volume 23, Issue 1, January 2019, Page 116-123 PDF (479.04 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/smj.2019.41367 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Al Hadad Ali Mousa1; Ahmed Mohammed Abd El-Mabood2; Hamza Abo-Alam Mahmoud2; Bahaa Refaie1 | ||||
| 1Department of Anesthesia, Faculty of Medicine, Sohag University. | ||||
| 2Department of Anesthesia, Faculty of Medicine,Sohag University. | ||||
| Abstract | ||||
| Hormonal stress response due to manipulation of the upper and lower respiratory tracts occurring during rigid bronchoscopy represents a potentially great hazard to safeanesthesia.There were many attempts to attenuate these adverse effects.Dexmedetomidine is highly selective, short-acting central alpha 2 agonist. It has increasingly gained popularity among anesthesiologists as adjuvant to general and regional anesthesia techniques. This study was conducted to compare the efficacy of administrating fentanyl, dexmedetomidine or lidocaine on control of hormonal changes in response to rigid bronchoscopy in pediatric patients. Ninety ASA I-II children aged 2-12 year were randomly assigned to 3 groups: fentanyl (F), dexmedetomidine (D) and lidocaine (Z). cortisol, ACTH and vasopressinlevels were measured and recorded. Results revealed that patients in the D group showed less elevation of ACTH levels in in response to the insertion of the rigid bronchoscope compared with the other groups, cortisol levels increased significantly after bronchoscopy in the lidocaine group, meanwhile, changes in vasopressin levels were not significant between the groups We concluded that dexmedetomidine can be used safely and effectively to attenuate the hormonal responses to rigid bronchoscopy in pediatric patients. | ||||
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