Evaluation of Intralesional Injection of Combined Furosemide and Digoxin Formula in the Treatment of Warts | ||||
| International Journal of Medical Arts | ||||
| Article 10, Volume 7, Issue 5, May 2025, Page 5722-5725 PDF (1.57 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ijma.2024.274694.1941 | ||||
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| Authors | ||||
Amr Abo El-Hassan Abbas  ; Atia Abdallah Atia; Ibrahim Mohamed Abdelsalam Abdelkarim
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| Department of Dermatology, Andrology and Venereology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||||
| Abstract | ||||
| Background: Warts are benign growths that appear on the skin or mucous membranes as a result of an infection with the human papillomavirus (HPV). Few prior investigations examined the efficacy of a topical combination of digoxin and furosemide for the treatment of warts. The study to assess and confirm the effectiveness of intralesional ionic antiviral injections that mix digoxin and furosemide for the treatment of multiple resistant plantar warts Patients and Methods: An interventional trial with two arms was conducted. Thirty plantar warts patients in all were chosen from the Al-Azhar University Hospital's outpatient clinics for dermatology, andrology, and venereology. Results: The mean number of sessions for the studied cases was 5.17 (±0.91 SD) with a range of 4-6. Of the studied cases, 23 (76.7%) had pain, 7 (23.3%) had hemorrhagic bulla and pain with a pain score of 6 (±2.36 SD), and 23 (100%) of completely treated cases had no recurrence. Of the studied cases, 2 (6.7%) had no response, 5 (16.7%) had partial clearance, and 23 (76.7%) had complete clearance. Following treatment, the largest wart's mean size was 0.14 (±0.34 SD) with a range of 0–1.5 and the mean number of warts was 0.43 (±0.86 SD) with a range of 0–3. We discovered a statistically significant relationship between the kind of clearance and the number of sessions, age, and duration of the condition. Conclusion: Our findings suggest that intralesional injection of digoxin and furosemide together is a successful treatment for numerous plantar warts. | ||||
| Keywords | ||||
| Warts; Intralesional Injections; Furosemide; Digoxin | ||||
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