cystatin C serum level and radiological findings in acute ischemic stroke
ismaeil, A., yousef, S., badawy, A., helal, R. (2021). cystatin C serum level and radiological findings in acute ischemic stroke. EKB Journal Management System, 27(1), 140-147. doi: 10.21608/zumj.2019.12875.1229
adham mahmoud ismaeil; Sawsan yousef; ahmed el sayed badawy; rania yehia helal. "cystatin C serum level and radiological findings in acute ischemic stroke". EKB Journal Management System, 27, 1, 2021, 140-147. doi: 10.21608/zumj.2019.12875.1229
ismaeil, A., yousef, S., badawy, A., helal, R. (2021). 'cystatin C serum level and radiological findings in acute ischemic stroke', EKB Journal Management System, 27(1), pp. 140-147. doi: 10.21608/zumj.2019.12875.1229
ismaeil, A., yousef, S., badawy, A., helal, R. cystatin C serum level and radiological findings in acute ischemic stroke. EKB Journal Management System, 2021; 27(1): 140-147. doi: 10.21608/zumj.2019.12875.1229

cystatin C serum level and radiological findings in acute ischemic stroke

Zagazig University Medical Journal
Article 16, Volume 27, Issue 1, January 2021, Page 140-147  XML PDF (944.95 K)
Document Type: Original Article
DOI: 10.21608/zumj.2019.12875.1229
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Authors
adham mahmoud ismaeil1; Sawsan yousef2; ahmed el sayed badawy3; rania yehia helal email 4
1professor of neurology,faculty of medicne,zagazig university,Egypt
2professor of neurology,neurology department,faculty of medicine ,zagazig university,Egypt
3assisstant professor at neurology department,faculty of medicine,zagazig university,Egypt
4assisstant lecturer at neurology department,faculty of medicine,zagazig university,Zagazig,Egypt
Abstract
Abstract:
Background: Cerebrovascular stroke is a costly disease. Cystatin C is an important biomarker for acute ischemic stroke due to the background of accumulating evidence indicating a link between vascular disease of the kidney and brain.
Aim: We investigated the association of serum cystatin C levels with radiological findings of first ever acute ischemic stroke.
Patients and methods: We included in this prospective cohort study 58 adult patients with first ever acute cerebrovascular ischemic stroke of not more than 72 hours duration with normal kidney functions (26 males and 32 females with age ranged from 33 to 90 years). Serum cystatin C level was measured by enzyme-linked immune-sorbent assay ( ELISA) . All patients were subjected to brain computed tomography (CT) scan to confirm the diagnosis of acute ischemic stroke and it was repeated after 48 hours.
Results: We found statistically significant positive correlation between cystatin C serum level and early signs of middle cerebral artery (MCA) infarction and size of infarction.
Conclusion: There is positive correlation between serum cystatin C level and size of infarction in acute ischemic stroke.
Keywords
Cystatin C; stroke; Infarct size
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