EVALUATION OF PHYTOCHEMICAL COMPOUNDS IN Moringa oliefera Lam. EXTRACTS ON CYTOTOXICITY OF MCF-7 CELL LINE | ||||
| Arab Universities Journal of Agricultural Sciences | ||||
| Article 2, Volume 27, Issue 1, March 2019, Page 17-26 PDF (1.12 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ajs.2019.43063 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Marwa S. Abd El Alem1; S. H. Ali2; M. I. Sarwat2; S. H. Hussein1 | ||||
| 1Medicinal and Aromatic Plants Dept., Horticulture Research Institute, Agriculture Research Center, Giza, Egypt | ||||
| 2Agric. Biochemistry Dept., Fac. of Agric., Ain Shams Univ., P.O. Box 68 Hadyek Shoubra 11241, Cairo, Egypt | ||||
| Abstract | ||||
| Moringa olifera Lam. which called "Miracle tree" was an enormous usage of medical, nutritional and economic benefits so its leaves and roots extracts were vitro examined for phytochemicals contents, antioxidant, and cytotoxicity against MCF-7 cell line. Leaves and roots both extracts were estimate using 2,2-di phenyl-1-picryl hydrazyl (DPPH) radical scavenging assay and high performance liquid chromatography (HPLC) to determine phenolic and flavonoids compounds. The leaves aqueous and ethyl acetate extracts contained a significantly (p<0.05) more phenolic compounds than root extracts, while roots ethyl acetate extracts were significantly more active in DPPH assay comparing with aqueous extracts . However, the leaves aqueous extract and roots ethyl extracts were contained high values flavonoids compound but in case of phenolic compounds the aqueous roots ex tract recorded the greatest highest number followed by the leaves ethyl acetate extract. The ethyl acetate extractions for leaves and roots have a high inhibition percentage against breast adenocarcinoma MCF-7 cell line comparing with aqueous extracts. | ||||
| Keywords | ||||
| antioxidant; MCF-7 cell line; HPLC; Moringa olifera leaves and roots; ethyl acetate extract | ||||
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