CORONARY ARTERY DISEASE AND SEGMENTAL ISOVOLUMIC RELAXATION PATTERNS- WHAT IS THE RELATION?
Abd El-Aziz, T., El-Dosouky, I., Al-Daydamony,, M. (2014). CORONARY ARTERY DISEASE AND SEGMENTAL ISOVOLUMIC RELAXATION PATTERNS- WHAT IS THE RELATION?. EKB Journal Management System, 20(1), 1-6. doi: 10.21608/zumj.2014.4347
Tarek Abd El-Aziz; Ibtesam El-Dosouky; Mohammad Al-Daydamony,. "CORONARY ARTERY DISEASE AND SEGMENTAL ISOVOLUMIC RELAXATION PATTERNS- WHAT IS THE RELATION?". EKB Journal Management System, 20, 1, 2014, 1-6. doi: 10.21608/zumj.2014.4347
Abd El-Aziz, T., El-Dosouky, I., Al-Daydamony,, M. (2014). 'CORONARY ARTERY DISEASE AND SEGMENTAL ISOVOLUMIC RELAXATION PATTERNS- WHAT IS THE RELATION?', EKB Journal Management System, 20(1), pp. 1-6. doi: 10.21608/zumj.2014.4347
Abd El-Aziz, T., El-Dosouky, I., Al-Daydamony,, M. CORONARY ARTERY DISEASE AND SEGMENTAL ISOVOLUMIC RELAXATION PATTERNS- WHAT IS THE RELATION?. EKB Journal Management System, 2014; 20(1): 1-6. doi: 10.21608/zumj.2014.4347

CORONARY ARTERY DISEASE AND SEGMENTAL ISOVOLUMIC RELAXATION PATTERNS- WHAT IS THE RELATION?

Zagazig University Medical Journal
Article 9, Volume 20, Issue 1, January 2014, Page 1-6  XML PDF (548.45 K)
Document Type: Original Article
DOI: 10.21608/zumj.2014.4347
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Authors
Tarek Abd El-Aziz1; Ibtesam El-Dosouky1; Mohammad Al-Daydamony,2
1Cardiology Departments. Zagazig university hospitals. Faculty of Medicine, Zagazig. Egypt.
2Cardiology Departments. Zagazig university hospitals. Faculty of Medicine, Zagazig. Egypt
Abstract
Background: Some segments relax with the early diastolic peak velocity lying in the isovolumic relaxation period. Its significance for prediction of coronary artery disease has not been fully elucidated. So we aimed to elucidate if the presence of abnormal isovolumic relaxation velocities can add a value to predict presence of significant coronary artery disease.
Methods: This study included 100consecutive subjects; 60 subjects with coronary artery disease (CAD), 40 normal subjects as a control group. Echocardiographic evaluation of: wall motion abnormalities, transmitral; E and A-velocities & E/A ratio. Tissue-Doppler study of the isovolumic relaxation velocities detected in the four basal segments. Patients with CAD were divided into; group I with significant CAD, group II with non significant CAD, the control group represents group III. Collected data underwent statistical analysis.
Result: post systolic shortening (PSS) was more frequent in the ischemic myocardium; with high specificity (92.5%) and good positive predictive value (86.6%) in detecting segments with significant coronary stenosis. The incidence of occurrence of peak early diastolic velocity (PVIVR) is more in patients with non significant CAD; it has good specificity (86.2%) for detection of any degree of coronary stenosis.
Conclusion: The presence of abnormal isovolumic relaxation velocities could be considered as a good positive test for prediction of CAD.
Keywords
Isovolumic relaxation velocity; Post systolic shortening (PSS); peak early diastolic velocity (PVIVR)
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