Cognitive Functions After Open Heart Surgeries: Comparison Between Inhalational And Total Intravenous Anesthesia
Kamel, R., Massoud, S., Salah, A., Abdel Ghani, A., Nada, E. (2021). Cognitive Functions After Open Heart Surgeries: Comparison Between Inhalational And Total Intravenous Anesthesia. EKB Journal Management System, 27(2), 247-256. doi: 10.21608/zumj.2019.14234.1299
Rania Ahmed Kamel; Samia Mohamed Massoud; Amal Abdel Azeem Salah; Alaa Ali Abdel Ghani; Eslam Nabil Nada. "Cognitive Functions After Open Heart Surgeries: Comparison Between Inhalational And Total Intravenous Anesthesia". EKB Journal Management System, 27, 2, 2021, 247-256. doi: 10.21608/zumj.2019.14234.1299
Kamel, R., Massoud, S., Salah, A., Abdel Ghani, A., Nada, E. (2021). 'Cognitive Functions After Open Heart Surgeries: Comparison Between Inhalational And Total Intravenous Anesthesia', EKB Journal Management System, 27(2), pp. 247-256. doi: 10.21608/zumj.2019.14234.1299
Kamel, R., Massoud, S., Salah, A., Abdel Ghani, A., Nada, E. Cognitive Functions After Open Heart Surgeries: Comparison Between Inhalational And Total Intravenous Anesthesia. EKB Journal Management System, 2021; 27(2): 247-256. doi: 10.21608/zumj.2019.14234.1299

Cognitive Functions After Open Heart Surgeries: Comparison Between Inhalational And Total Intravenous Anesthesia

Zagazig University Medical Journal
Article 176, Volume 27, Issue 2, March 2021, Page 247-256  XML PDF (620.88 K)
Document Type: Original Article
DOI: 10.21608/zumj.2019.14234.1299
View on SCiNiTO View on SCiNiTO
Authors
Rania Ahmed Kamel email 1; Samia Mohamed Massoud2; Amal Abdel Azeem Salah3; Alaa Ali Abdel Ghani4; Eslam Nabil Nada2
1Anesthesia and Surgical Intensive Care department,Faculty of Medicine,Zagazig University,Zagazig,Egypt
2Anesthesia & Surgical Intensive Care department,Faculty of Medicine,Zagazig University,Zagazig,Egypt
3Anesthesia & Surgical Intensive Care department,Faculty of Medicine,Zagazig UniversityZagazig,Egypt
4Neurology department,Faculty of Medicine,Zagazig University,Zagazig,Egypt
Abstract
Abstract:
Background: Postoperative cognitive dysfunction (POCD) is a frequent significant complication post-cardiac surgery. Quoted incidences are dependent on variable factors: timing of measurements, the type of surgery, the exact assessment used, and its sensitivity. The role of anesthetic agent in POCD is still uncertain.
Objective: to study the cognitive functions after isoflurane- compared with propofol-based anesthesia for open heart surgeries.
Patients and Methods: In this prospective study, 260 patients undergoing elective open heart surgery were included and allocated into 2 equal groups: isoflurane-based anesthesia and propofol-based anesthesia. POCD was defined as deterioration ≥ 20% from baseline in at least 2 of the neurocognitive tests. Battery of seven neurocognitive tests was applied to assess the patients before and 3 to 7 days after surgery.
Results: The incidence of POCD in our study was 43.6%, with no significant difference between both isoflurane group (38.4%) and propofol group (48.8%), P=0.097. POCD had a significant association with: age, body mass index, educationa level, hypertension, diabetes, type of surgery, ejection fraction, time of operation, cardiopulmonary bypass (CPB) time, aortic cross clamp (ACC) time and intraoperative complication. However, only low educational level (P=0.013) and ACC time (P
Keywords
Cognitive dysfunction; Isoflurane; propofol; Open heart surgery
Statistics
Article View: 285
PDF Download: 210