PREVALENCE OF HEPATITIS C INFECTION AMONG DIABETICS TYPE 2 AT SHARKIA GOVERNORATE, EGYPT
Amin, E., Ghorab, A., Mohamed, M., Zidan, A. (2015). PREVALENCE OF HEPATITIS C INFECTION AMONG DIABETICS TYPE 2 AT SHARKIA GOVERNORATE, EGYPT. EKB Journal Management System, 21(1), 1-10. doi: 10.21608/zumj.2015.4458
Essam Amin; Adel Ghorab; Mohamed Mohamed; Amal Zidan. "PREVALENCE OF HEPATITIS C INFECTION AMONG DIABETICS TYPE 2 AT SHARKIA GOVERNORATE, EGYPT". EKB Journal Management System, 21, 1, 2015, 1-10. doi: 10.21608/zumj.2015.4458
Amin, E., Ghorab, A., Mohamed, M., Zidan, A. (2015). 'PREVALENCE OF HEPATITIS C INFECTION AMONG DIABETICS TYPE 2 AT SHARKIA GOVERNORATE, EGYPT', EKB Journal Management System, 21(1), pp. 1-10. doi: 10.21608/zumj.2015.4458
Amin, E., Ghorab, A., Mohamed, M., Zidan, A. PREVALENCE OF HEPATITIS C INFECTION AMONG DIABETICS TYPE 2 AT SHARKIA GOVERNORATE, EGYPT. EKB Journal Management System, 2015; 21(1): 1-10. doi: 10.21608/zumj.2015.4458

PREVALENCE OF HEPATITIS C INFECTION AMONG DIABETICS TYPE 2 AT SHARKIA GOVERNORATE, EGYPT

Zagazig University Medical Journal
Article 5, Volume 21, Issue 1, January 2015, Page 1-10  XML PDF (643.12 K)
Document Type: Original Article
DOI: 10.21608/zumj.2015.4458
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Authors
Essam Amin1; Adel Ghorab1; Mohamed Mohamed2; Amal Zidan3
1Internal Medicine Departments, Faculty of Medicine,Zagazig University Hospital, Egypt
2Internal Medicine Departments, Faculty of Medicine,Zagazig University Hospital, Egypt
3Clinical Pathology Departments, Faculty of Medicine,Zagazig University Hospital, Egypt
Abstract
Background: HCV virus infection and type 2 diabetes mellitus are two major public health problems in Egypt. Egypt has the highest HCV virus prevalence in the world and is considered the ninth in rank of the highest prevalence of diabetes worldwide. The mutual relationship between diabetes and increased HCV infection may be due to the association of HCV with hepatic steatosis, insulin resistance and decrease of adiponectine synthesis as well as the nature of diabetes and its inherent complications and/or frequent parental exposure. Objective: determination of the prevalence of HCV infection in type-2 diabetics in Sharkia Governorate and to explore the predominant risk factors for HCV infection and its relation to some demographic parameters of this locality. Subjects and methods: A cross sectional randomized study was conducted to 642 patients, regardless of gender, body weight, educational level or socioeconomic levels, at multicentre managing diabetic patients at Sharkia governorate. All patients were subjected to detection of HCV-ab by third generation ELISA and HBA1C level
Results:
The prevalence of HCV infection among type 2 diabetic patients at Sharkia governorate approximates 38.7 %. Higher prevalence was detected among patients between 45 & 65 years old, low socioeconomic level, low educational level, and those who share personal utensils, have other family members infected with HCV. Patients who previously transfused, previous hospitalized, previously received parenteral anti-bilharzial therapy and those receiving insulin injections are also at high risk. Conclusion: As high as 39% of type-2 diabetics at Sharkia Governorate are HCV-infected. Apart from classic risk factors, The most significant independable factors associated with development of HCV infection in type 2 diabetics are low socioeconomic standard and low educational level. Previous blood transfusion, family members infected with HCV, parenteral antibilharzial treatment, sharing personal utensils and previous hospitalization may play also a role.
Keywords
Hepatitis C virus; Type 2 Diabetes; prevalence
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