SENTINEL LYMPH NODES DISSECTION VERSUS AXILLARY LYMPH NODES DISSECTION IN PATIENTS WITH EARLY BREAST CANCER AND SENTINEL NODES METASTASES
Hamrah, N., Khalil, A., Abdel-Aal, M., Ismail, N., Baiomy, T., Hussien, I. (2015). SENTINEL LYMPH NODES DISSECTION VERSUS AXILLARY LYMPH NODES DISSECTION IN PATIENTS WITH EARLY BREAST CANCER AND SENTINEL NODES METASTASES. EKB Journal Management System, 21(1), 1-7. doi: 10.21608/zumj.2015.4464
Nabil Hamrah; Alaa Khalil; Mohammed Abdel-Aal; Nadia Ismail; Taha Baiomy; Ibtsam Hussien. "SENTINEL LYMPH NODES DISSECTION VERSUS AXILLARY LYMPH NODES DISSECTION IN PATIENTS WITH EARLY BREAST CANCER AND SENTINEL NODES METASTASES". EKB Journal Management System, 21, 1, 2015, 1-7. doi: 10.21608/zumj.2015.4464
Hamrah, N., Khalil, A., Abdel-Aal, M., Ismail, N., Baiomy, T., Hussien, I. (2015). 'SENTINEL LYMPH NODES DISSECTION VERSUS AXILLARY LYMPH NODES DISSECTION IN PATIENTS WITH EARLY BREAST CANCER AND SENTINEL NODES METASTASES', EKB Journal Management System, 21(1), pp. 1-7. doi: 10.21608/zumj.2015.4464
Hamrah, N., Khalil, A., Abdel-Aal, M., Ismail, N., Baiomy, T., Hussien, I. SENTINEL LYMPH NODES DISSECTION VERSUS AXILLARY LYMPH NODES DISSECTION IN PATIENTS WITH EARLY BREAST CANCER AND SENTINEL NODES METASTASES. EKB Journal Management System, 2015; 21(1): 1-7. doi: 10.21608/zumj.2015.4464

SENTINEL LYMPH NODES DISSECTION VERSUS AXILLARY LYMPH NODES DISSECTION IN PATIENTS WITH EARLY BREAST CANCER AND SENTINEL NODES METASTASES

Zagazig University Medical Journal
Article 11, Volume 21, Issue 1, January 2015, Page 1-7  XML PDF (770.37 K)
Document Type: Original Article
DOI: 10.21608/zumj.2015.4464
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Authors
Nabil Hamrah1; Alaa Khalil1; Mohammed Abdel-Aal1; Nadia Ismail1; Taha Baiomy2; Ibtsam Hussien2
1General Surgery Department, Faculty of Medicine, Zagazig University.
2General Surgery Department, Faculty of Medicine, Zagazig University
Abstract
Background: Sentinel lymph node biopsy (SLNB) has become the standard method for axillary staging of breast cancer with reliable accuracy and less morbidity compared with axillary lymph node dissection (ALND) aiming to minimize the rate of patients with negative axillary status who undergo ALND and restricted only to patients with positive axillary lymph node.
Objective: To compare the results of SLN dissection only and that of ALN dissection regarding the morbidity and locoregional recurrence.
Patients and methods: A hundred patients with histologically confirmed invasive breast cancer T1/T2N0M0 and SLN positive for metastases (≤3 SLNs) were entered the study and divided randomly into two groups. Group I: Fifty (50) patients underwent SLN dissection only. Group II: Fifty (50) patients underwent SLN dissection and ALN dissection.
Exclusion criteria: Patients with >3 positive SLNs, patients with matted nodes, patients with gross extranodal disease and patients received neoadjuvant hormonal therapy or chemotherapy.
Statistical analysis: SPSS version 15.
Results: Adverse surgical effects were reported in both groups. In SLND group (6%) had seroma while in ALND group (16%) had seroma, wound infection was (4%) in SLND and (8%) in ALND, postoperative parasthesia after 1 year was (16%) in SLND and (44%) in ALND, postoperative lymphoedema after 1 year was (4%) in SLND and (10%) in ALND and axillary recurrence was (2%) in SLND and no recurrence in ALND.
Conclusion: SLND mapping and excision is the standard of care for axillary staging for patients with early invasive breast cancer and clinically node-negative disease.
Keywords
Early breast cancer; clinically node-negative; SLND and ALND
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