Assessment of Neutrophil Lymphocyte Ratio in Systemic Sclerosis Patients in Tanta University Hospital: A Promising Marker in Predicting Disease Severity | ||||
| Egyptian Journal of Rheumatology and Clinical Immunology | ||||
| Article 7, Volume 4, Issue 1, January 2016, Page 33-41 PDF (118.19 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejrci.2015.4475 | ||||
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| Authors | ||||
| Noha Esheba; Abeer Shahba | ||||
| Department of Internal Medicine, Tanta University; Egypt | ||||
| Abstract | ||||
| Introduction: Systemic sclerosis (SSc) is a multisystem autoimmune disease, with complex pathogenesis resulting in obliterative vasculopathy, tissue injury, fibrosis, remodeling and atrophy. The neutrophil lymphocyte ratio (NLR) was developed to provide easily measurable and readily available parameter reflecting the intensity of stress and systemic inflammation in critically ill patients following shock, multiple traumas, major surgery, or sepsis. Aim of the work: to evaluate NLR levels in patients with SSc and explore their clinical significance and their association with different organ manifestations. Results: There was a significant increase in NLR in SSc patients who had cardiovascular or cardiorespiratory affection. Also NLR showed a significant positive correlation with both CRP and ESR, while it showed a significant negative correlation with serum albumin. Conclusion: NLR may serve as a promising marker for cardiorespiratory involvement in SSc patients. [Egypt J Rheumatology & Clinical Immunology, 2016; 4(1): 43-47] | ||||
| Keywords | ||||
| Systemic sclerosis; Neutrophil lymphocyte ratio; SSc; NLR | ||||
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