Serum Anti-Mullerian Hormone, Follicle Stimulating Hormone and Antral Follicle Count Measurement as a Prediction for Pregnancy Rates in IVF/ICSI cycle
Zakaria, A., Yosef, E., Deif, O., Khalil, M. (2019). Serum Anti-Mullerian Hormone, Follicle Stimulating Hormone and Antral Follicle Count Measurement as a Prediction for Pregnancy Rates in IVF/ICSI cycle. EKB Journal Management System, 77(1), 4692-4699. doi: 10.21608/ejhm.2019.45936
Abd El Monem Mohamed Zakaria; Ebrahim Hasan Mohamed Yosef; Osama Mohamed Deif; Mohammed Mahmoud Ahmed Khalil. "Serum Anti-Mullerian Hormone, Follicle Stimulating Hormone and Antral Follicle Count Measurement as a Prediction for Pregnancy Rates in IVF/ICSI cycle". EKB Journal Management System, 77, 1, 2019, 4692-4699. doi: 10.21608/ejhm.2019.45936
Zakaria, A., Yosef, E., Deif, O., Khalil, M. (2019). 'Serum Anti-Mullerian Hormone, Follicle Stimulating Hormone and Antral Follicle Count Measurement as a Prediction for Pregnancy Rates in IVF/ICSI cycle', EKB Journal Management System, 77(1), pp. 4692-4699. doi: 10.21608/ejhm.2019.45936
Zakaria, A., Yosef, E., Deif, O., Khalil, M. Serum Anti-Mullerian Hormone, Follicle Stimulating Hormone and Antral Follicle Count Measurement as a Prediction for Pregnancy Rates in IVF/ICSI cycle. EKB Journal Management System, 2019; 77(1): 4692-4699. doi: 10.21608/ejhm.2019.45936

Serum Anti-Mullerian Hormone, Follicle Stimulating Hormone and Antral Follicle Count Measurement as a Prediction for Pregnancy Rates in IVF/ICSI cycle

The Egyptian Journal of Hospital Medicine
Article 4, Volume 77, Issue 1, October 2019, Page 4692-4699  XML PDF (640.9 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2019.45936
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Authors
Abd El Monem Mohamed Zakaria1; Ebrahim Hasan Mohamed Yosef2; Osama Mohamed Deif1; Mohammed Mahmoud Ahmed Khalil email 2
1Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University
2Department of Pathology, Faculty of Medicine, Al-Azhar University
Abstract
Background: A successful in vitro fertilization treatment depends on the ability of the ovary to respond to gonadotrophin stimulation. This response reflects the ovarian function or ‘ovarian reserve’. Poor ovarian response may be associated with reduced number of oocytes and embryos and may lead to cycle cancellation in severe cases. On the other hand, exaggerated response leads to increased risk of ovarian hyper-stimulation syndrome. Objective: The aim of this study is to assess role of serum AMH, FSH and AFC measurement as a prediction of pregnancy rates in IVF/intracytoplasmic sperm injection (ICSI) cycle. Patients and Methods: A prospective cross sectional study was conducted at Specialized Air Forced Hospital in the period between January 2018 and December 2018. The study included 100 unexplained infertility patients undergoing IVF/ICSI treatment cycles. They were 82 patients primary infertility and 18 patients secondary infertility. Results: Type of infertility showed insignificant difference between the 2 groups while menstrual history and gonadotrophins type showed significant difference. Age and duration of infertility were significantly higher in nonpregnant group than pregnant. The mean value of FSH, day 3 E2 levels did not have any significant difference between the 2 group while the mean value of serum E2 the day of HCG injection, serum AMH day 3, AFC were significantly higher in pregnant group than non-pregnant. Conclusion: No test can predict pregnancy in high accuracy as it is multifactorial however, mean levels of FSH, E2, a day HCG injection and AFC showed significant difference between pregnant and non-pregnant.
Keywords
Anti-Mullerian hormone; Follicle Stimulating Hormone; Antral Follicle; Pregnancy Rates; IVF/ICSI cycle
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