The Role of 131I SPECT-CT as a Diagnostic Tool in Management of Patients with Differentiated Thyroid Cancer | ||||
| Egyptian Journal Nuclear Medicine | ||||
| Article 6, Volume 15, Issue 15, December 2017, Page 67-78 PDF (319.2 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/egyjnm.2017.46224 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Nadia M. Mekkawy; M. Mohamed, W. | ||||
| Clinical Oncology and Nuclear Medicine Department, faculty of medicine, Assiut University. | ||||
| Abstract | ||||
| purpose of the study was to estimate the value of using of 131I single photon emission tomography – computed tomography (SPECT/CT) in differentiated thyroid carcinoma (DTC) for diagnoses and follow up. Methods: Eighty-seven planar whole body scan (WBS) and SPECT/CT neck and chest were obtained for 77 pathologically proved DTC patients (17 males and 60 females; age range, 14 – 79 years). Fifty-two scans were 131I diagnostic (Dx) follow up studies, and 35 scans were 131I post-therapy (Rx) studies. Results: Planar scans depicted 106 foci in 45 studies (61 in the neck and 45 in distant sites); SPECT/CT scans depicted 125 foci in 51 studies (72 in the neck and 53 indistant sites), and characterized 16 indeterminate foci on planar scans in 13 /45 positive planar studies (28.9%). Both Planar and SPECT-CT scans were concurrently positive in 45 studies (51.7%), concurrently negative in 36 studies (41.4%), and discordant in 6 studies (6.9%). The incremental diagnostic value of SPECT-CT over planar imaging was obtained for approximately 30 % of detected lesions. Conclusion: SPECT/CT had better diagnostic information compared with planar whole body imaging. It correctly modified the risk classification defined by planar imaging and allowed for avoidance of unnecessary radioiodine (RI) treatment. | ||||
| Keywords | ||||
| SPECT-CT & Differentiated Thyroid Cancer | ||||
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