The Relation between Hemoglobin Level Variability and Carotid Intima-Media Thickness in Chronic Hemodialysis Patients
Abd elhamed Mohamed, M., arafa, A., anany metwaly, E. (2020). The Relation between Hemoglobin Level Variability and Carotid Intima-Media Thickness in Chronic Hemodialysis Patients. EKB Journal Management System, 26(5), 869-876. doi: 10.21608/zumj.2019.13873.1267
Mohamed Atef Abd elhamed Mohamed; ayman fathy arafa; elsayed anany metwaly. "The Relation between Hemoglobin Level Variability and Carotid Intima-Media Thickness in Chronic Hemodialysis Patients". EKB Journal Management System, 26, 5, 2020, 869-876. doi: 10.21608/zumj.2019.13873.1267
Abd elhamed Mohamed, M., arafa, A., anany metwaly, E. (2020). 'The Relation between Hemoglobin Level Variability and Carotid Intima-Media Thickness in Chronic Hemodialysis Patients', EKB Journal Management System, 26(5), pp. 869-876. doi: 10.21608/zumj.2019.13873.1267
Abd elhamed Mohamed, M., arafa, A., anany metwaly, E. The Relation between Hemoglobin Level Variability and Carotid Intima-Media Thickness in Chronic Hemodialysis Patients. EKB Journal Management System, 2020; 26(5): 869-876. doi: 10.21608/zumj.2019.13873.1267

The Relation between Hemoglobin Level Variability and Carotid Intima-Media Thickness in Chronic Hemodialysis Patients

Zagazig University Medical Journal
Article 215, Volume 26, Issue 5, September 2020, Page 869-876  XML PDF (507.49 K)
Document Type: Original Article
DOI: 10.21608/zumj.2019.13873.1267
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Authors
Mohamed Atef Abd elhamed Mohamed email 1; ayman fathy arafa2; elsayed anany metwalyorcid 3
1Internal medicine..alahrar teaching hospital
2internal medicine,faculty of medicine,zagazig university
3internal medicine,facultyof medicine,zagazig university
Abstract
Background: Hemoglobin variability (HB), defined as hemoglobin value varying between low, normal and high levels, is a common condition among hemodialysis (HD) patients. Atherosclerotic lesions are highly prevalent in patients with chronic kidney disease (CKD). Carotid artery Intima-Media Thickness (CIMT) is noninvasive ultrasound test recommended to screen for heart disease
Aim: to evaluate the relation between Hemoglobin variability and CIMt among the studied patients
Patients and methods: A cross-sectional study was conducted on 70 patients on (HD) attending HD units in Internal Medicine Department in Zagazig University Hospitals and Al- Ahrar teaching hospital during the period from February 2018 to February 2019. Patients underwent history taking, clinical examination, and laboratory investigations. Efficiency of hemodialysis was calculated. CIMT is measured in B-mode ultrasound image using Doppler on carotid arteries.
Results: A significant positive correlation is detected between hemoglobin change and both CIMT and total cholesterol. However, there is significant negative correlation between hemoglobin change and hematocrit level. A significant negative correlation is present between CIMT and hematocrit value, total protein and CRP. A significant positive correlation is present between CIMT and serum albumin, serum creatinine, BUN and total cholesterol. The best cutoff of hemoglobin variability in prediction of abnormal CIMT is ≥3.45, with sensitivity 86.7%, specificity 90.9%, positive predictive value 72.2%, negative predictive value 96.1% with accuracy 90% (p < /p>
Keywords
Hemodialysis; Hemoglobin; variability
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