Cardiac Status in Hepatitis B Virus and Hepatocellular Carcinoma in Egyptian Adolescents | ||||
| Biochemistry Letters | ||||
| Article 16, Volume 13, Issue 1, 2017, Page 198-208 PDF (567.81 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/blj.2017.47610 | ||||
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| Authors | ||||
| Waleed Mohamed Serag1; Eman Mohamed Elsayed2 | ||||
| 1Chemistry Department, Faculty of Science, Suez University, Suez, Egypt | ||||
| 2Pediatric department, Faculty of Medicine, Ain Shams University, Cairo, Egypt | ||||
| Abstract | ||||
| Hepatitis B virus (HBV) is the major risk factor of hepatocellular carcinoma (HCC) in all age groups. There is a need to find the effect of them on the cardiac status in adolescence age by laboratory and physical examination for assessment of different outcomes of both diseases. Cross sectional study included 15 adolescents with HBV, another 15 with HBV complicated by HCC and 15 healthy persons served as control with age range 12 up to 18 years (14.4±3.58). They were selected for laboratory interleukin 6 (IL-6), Troponine I and Creatin Kinase MB fraction (CK MB) testing and further were examined at the Cardiology Unit in Pediatric department of Ain Shams University hospitals for complete echocardiographic and anthropometric evaluation. 15 patients have HCC with HBV were examined with mean age 14.15±3.01 years and another 15 are having HCV (14.64±4.13 years). The duration of HCC was 2.16 ± 2.89 years while the exposure of HBV was 2.27 ±3.35 years in the HCV group. Differences were found between both groups regards IL-6 as mean values were 0.26 pg/ml in HBV and 0.721 pg/ml in HCC group while no differences between groups were detected regards cardiac markers ; troponine I and CK MB and anthropometric evaluations. In adolescent patients with HBV and HBV with HCC , there is no change in the cardiac status. | ||||
| Keywords | ||||
| Hepatitis B virus; Hepatocellular carcinoma; Adolescents; Troponine I; Creatin Kinase MB; IL-6; Anthropometry; Echocardiography | ||||
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